N-Arachidonyl maleimide

Discontinued Product

N-Arachidonyl maleimide (Cat. No. 3329) has been withdrawn from sale for commercial reasons.
Cat.No. 3329 - N-Arachidonyl maleimide | C24H35NO2 | CAS No. 876305-42-9
Description: Potent, competitive MAGL inhibitor
Chemical Name: 1-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraen-1-yl-1H-pyrrole-2,5-dione
Purity: ≥98% (HPLC)
Literature (2)

Biological Activity

Potent, competitive and irreversible monoacylglycerol lipase (MAGL) inhibitor (IC50 = 140 nM). Selectively prevents metabolic inactivation of 2-arachidonoylglycerol (2-AG) by ~ 85% and increases the potency of 2-AG in mouse cerebellum in vitro.

Technical Data

M. Wt 369.54
Formula C24H35NO2
Storage Store at -80°C
Purity ≥98% (HPLC)
CAS Number 876305-42-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis / Product Datasheet
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Keywords: N-Arachidonyl maleimide, N-Arachidonyl maleimide supplier, Potent, competitive, MAGL, inhibitors, inhibits, Monoacylglycerol, Lipases, Esterases, MGL, 3329, Tocris Bioscience

Citations for N-Arachidonyl maleimide

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