Discontinued ProductN-Arachidonyl maleimide (Cat. No. 3329) has been withdrawn from sale for commercial reasons.
Potent, competitive and irreversible monoacylglycerol lipase (MAGL) inhibitor (IC50 = 140 nM). Selectively prevents metabolic inactivation of 2-arachidonoylglycerol (2-AG) by ~ 85% and increases the potency of 2-AG in mouse cerebellum in vitro.
|Storage||Store at -80°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Saario et al (2005) Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes. Chem.Biol. 12 649 PMID: 15975510
Blankman et al (2007) A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. Chem.Biol. 14 1347 PMID: 18096503
Burston et al (2008) N-arachidonyl maleimide potentiates the pharmalocogical and biochemical effects of the endocannabinoid 2-arachidonylyglycerol through inhibition of monoacylglycerol lipase. J.Pharmacol.Exp.Ther. 327 546 PMID: 18682568
View Related Products by Product Action
Keywords: N-Arachidonyl maleimide, N-Arachidonyl maleimide supplier, Potent, competitive, MAGL, inhibitors, inhibits, Monoacylglycerol, Lipases, Esterases, MGL, 3329, Tocris Bioscience
Citations for N-Arachidonyl maleimide
Citations are publications that use Tocris products.
Currently there are no citations for N-Arachidonyl maleimide.
Reviews for N-Arachidonyl maleimide
There are currently no reviews for this product. Be the first to review N-Arachidonyl maleimide and earn rewards!
Have you used N-Arachidonyl maleimide?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.