N-Acetyltryptamine

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Cat.No. 0357 - N-Acetyltryptamine | C12H14N2O | CAS No. 1016-47-3
Description: Substrate for serotonin N-acetyl transferase
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

A partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.

Compound Libraries

N-Acetyltryptamine is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 202.26
Formula C12H14N2O
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 1016-47-3
PubChem ID 70547
InChI Key NVUGEQAEQJTCIX-UHFFFAOYSA-N
Smiles CC(=O)NCCC1=CNC2=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 20.23 100
DMSO 20.23 100

Preparing Stock Solutions

The following data is based on the product molecular weight 202.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.94 mL 24.72 mL 49.44 mL
5 mM 0.99 mL 4.94 mL 9.89 mL
10 mM 0.49 mL 2.47 mL 4.94 mL
50 mM 0.1 mL 0.49 mL 0.99 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Dubocovich (1985) Characterization of a retinal melatonin receptor. J.Pharmacol.Exp.Ther. 234 395 PMID: 2991499

Dubocovich (1988) Luzindole (NO 774): a novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 246 902 PMID: 2843633

Dubocovich (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50 PMID: 7762083

Thomas et al (1990) Arylalkylamine (serotonin) N-acetyl transferase assay using high-performance liquid-chromatography with fluorescence or electrochemical detection of N-acetyltryptamine. Anal.Biochem. 184 228 PMID: 2327568


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Citations for N-Acetyltryptamine

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Literature in this Area

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