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Cat.No. 0357 - N-Acetyltryptamine | C12H14N2O | CAS No. 1016-47-3
Description: Substrate for serotonin N-acetyl transferase
Purity: ≥99% (HPLC)

Biological Activity

A partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.

Compound Libraries

N-Acetyltryptamine is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 202.26
Formula C12H14N2O
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 1016-47-3
PubChem ID 70547
Smiles CC(=O)NCCC1=CNC2=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 20.23 100
ethanol 20.23 100

Preparing Stock Solutions

The following data is based on the product molecular weight 202.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.94 mL 24.72 mL 49.44 mL
5 mM 0.99 mL 4.94 mL 9.89 mL
10 mM 0.49 mL 2.47 mL 4.94 mL
50 mM 0.1 mL 0.49 mL 0.99 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet


References are publications that support the products' biological activity.

Dubocovich (1985) Characterization of a retinal melatonin receptor. J.Pharmacol.Exp.Ther. 234 395 PMID: 2991499

Dubocovich (1988) Luzindole (NO 774): a novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 246 902 PMID: 2843633

Dubocovich (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50 PMID: 7762083

Thomas et al (1990) Arylalkylamine (serotonin) N-acetyl transferase assay using high-performance liquid-chromatography with fluorescence or electrochemical detection of N-acetyltryptamine. Anal.Biochem. 184 228 PMID: 2327568

If you know of a relevant reference for N-Acetyltryptamine, please let us know.

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