A partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 202.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.94 mL||24.72 mL||49.44 mL|
|5 mM||0.99 mL||4.94 mL||9.89 mL|
|10 mM||0.49 mL||2.47 mL||4.94 mL|
|50 mM||0.1 mL||0.49 mL||0.99 mL|
References are publications that support the products' biological activity.
Dubocovich (1985) Characterization of a retinal melatonin receptor. J.Pharmacol.Exp.Ther. 234 395 PMID: 2991499
Dubocovich (1988) Luzindole (NO 774): a novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 246 902 PMID: 2843633
Dubocovich (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50 PMID: 7762083
Thomas et al (1990) Arylalkylamine (serotonin) N-acetyl transferase assay using high-performance liquid-chromatography with fluorescence or electrochemical detection of N-acetyltryptamine. Anal.Biochem. 184 228 PMID: 2327568
If you know of a relevant reference for N-Acetyltryptamine, please let us know.
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Keywords: N-Acetyltryptamine, supplier, Melatonin, partial, agonists, MT1, MT2, MT3, antagonists, Serotonin, N-acetyltransferase, Substrate, serotonin, N-acetyl, transferase, MT, Receptors, 5-HT3, 5-Hydroxytryptamine, 5-HT, Transferases, activators, Melatonin, (MT), Receptors, 5-HT-Related, Enzyme, Substrates, /, Activators, 5-HT3, Receptors, Other, Transferases, Other, Transferases, Tocris Bioscience
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Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.
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