N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide

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Cat.No. 1930 - N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide | N-Ac-pTyr-Glu-dipentylamide | CAS No. 190078-50-3
Description: Phosphopeptide ligand for src SH2 domain
Chemical Name: N-Acetyl-O-phosphono-L-tyrosyl-N,N-dipentyl-L-α-glutamine
Datasheet
Citations
Literature

Biological Activity

Phosphopeptide; binds to the src SH2 domain.

Technical Data

M. Wt 571.61
Formula C26H42N3O9P
Sequence YE

(Modifications: Tyr-1 = N-Ac-p-Tyr, Glu-2 = Glu-dipentylamide)

Storage Desiccate at -20°C
CAS Number 190078-50-3
PubChem ID 444112
InChI Key LMADZBIAOYLZDD-GOTSBHOMSA-N
Smiles OC(CC[C@@H]([C@@](N(CCCCC)CCCCC)=O)NC([C@@H](NC(C)=O)CC1=CC=C(OP(O)(O)=O)C=C1)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 571.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.75 mL 8.75 mL 17.49 mL
5 mM 0.35 mL 1.75 mL 3.5 mL
10 mM 0.17 mL 0.87 mL 1.75 mL
50 mM 0.03 mL 0.17 mL 0.35 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Charifson et al (1997) Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry 36 6283 PMID: 9174343

Pacofsky et al (1998) Potent dipeptide inhibitors of the pp60c-src SH2 domain. J.Med.Chem. 41 1894 PMID: 9599239


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View all Src Kinase Ligands

Keywords: Phosphopeptide ligands src SH2 domain Kinases Src Kinases

Citations for N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide

Citations are publications that use Tocris products.

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Pathways for N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide

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