N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide

Discontinued Product

N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide (Cat. No. 1930) has been withdrawn from sale for commercial reasons.
Description: Phosphopeptide ligand for src SH2 domain
Chemical Name: N-Acetyl-O-phosphono-L-tyrosyl-N,N-dipentyl-L-α-glutamine

Biological Activity

N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide is a phosphopeptide; binds to the src SH2 domain.

Technical Data

M. Wt 571.61
Formula C26H42N3O9P
Sequence YE

(Modifications: Tyr-1 = N-Ac-p-Tyr, Glu-2 = Glu-dipentylamide)

Storage Desiccate at -20°C
CAS Number 190078-50-3
PubChem ID 444112
Smiles OC(CC[C@@H]([C@@](N(CCCCC)CCCCC)=O)NC([C@@H](NC(C)=O)CC1=CC=C(OP(O)(O)=O)C=C1)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.


References are publications that support the biological activity of the product.

Charifson et al (1997) Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry 36 6283 PMID: 9174343

Pacofsky et al (1998) Potent dipeptide inhibitors of the pp60c-src SH2 domain. J.Med.Chem. 41 1894 PMID: 9599239

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Keywords: N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide, N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide supplier, Phosphopeptide, ligands, src, SH2, domain, Kinases, Src, 1930, Tocris Bioscience

Citations for N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide

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Currently there are no citations for N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide.

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