N-(4-Hydroxyphenylacetyl)spermine

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Cat.No. 0290 - N-(4-Hydroxyphenylacetyl)spermine | C18H32N4O2 | CAS No. 130210-32-1
Description: Wasp toxin analog
Chemical Name: N-(N-(4-Hydroxyphenylacetyl)-3-aminopropyl)-(N'-3-aminopropyl)-1,4-butanediamine
Datasheet
Citations
Literature

Biological Activity

Wasp toxin analog. More potent than PhTX-343 at locust NMJ. Reported to be selective for NMDA receptors in mammalian CNS.

Technical Data

M. Wt 336.48
Formula C18H32N4O2
Storage Desiccate at -20°C
CAS Number 130210-32-1
PubChem ID 14622098
InChI Key DRHUIJOIIKXHEH-UHFFFAOYSA-N
Smiles OC1=CC=C(CC(NCCCNCCCCNCCCN)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in water

Preparing Stock Solutions

The following data is based on the product molecular weight 336.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.97 mL 14.86 mL 29.72 mL
5 mM 0.59 mL 2.97 mL 5.94 mL
10 mM 0.3 mL 1.49 mL 2.97 mL
50 mM 0.06 mL 0.3 mL 0.59 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service.
Safety Datasheet

References

References are publications that support the products' biological activity.

Bycroft et al (1990) Invertebrate pharmacological assay of novel, potent glutamate antagonists: acylated spermines. Eur.J.Pharmacol. 183 470 PMID:

Smith et al (1990) Mono-acylated spermines: antagonists of glutamate receptors. Eur.J.Pharmacol. 183 472 PMID:


If you know of a relevant reference for N-(4-Hydroxyphenylacetyl)spermine, please let us know.

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Keywords: N-(4-Hydroxyphenylacetyl)spermine, supplier, Wasp, toxin, Glutamate, NMDA, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, NMDA, Receptors, Tocris Bioscience

Citations for N-(4-Hydroxyphenylacetyl)spermine

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