N-(3-Oxododecanoyl)-L-homoserine lactone

Discontinued Product

N-(3-Oxododecanoyl)-L-homoserine lactone (Cat. No. 6548) has been withdrawn from sale for commercial reasons.
Description: Bacterial quorum sensing autoinducer; immunomodulator
Chemical Name: 3-Oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]dodecanamide
Datasheet
Citations
Reviews

Biological Activity

N-(3-Oxododecanoyl)-L-homoserine lactone is a bacterial quorum sensing signal molecule. Inhibits lymphocyte proliferation and TNF-α and IL-12 production by LPS-stimulated macrophages. Inhibits or promotes antibody production at high and low concentrations, respectively, in keyhole limpet hemocyanin (KLH)-stimulated spleen cells. Immunomodulator.

Technical Data

M. Wt 297.39
Formula C16H27NO4
Storage Store at -20°C
CAS Number 168982-69-2
PubChem ID 3246941
InChI Key PHSRRHGYXQCRPU-AWEZNQCLSA-N
Smiles CCCCCCCCCC(CC(N[C@H]1CCOC1=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References

References are publications that support the biological activity of the product.

Telford et al (1998) The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone has immunomodulatory activity. Infect.Immun. 66 36 PMID: 9423836

View Related Products by Target

Keywords: N-(3-Oxododecanoyl)-L-homoserine lactone, N-(3-Oxododecanoyl)-L-homoserine lactone supplier, OdDHL, quorum, sensing, sensors, autoinducers, Gram-negative, bacterial, Pseudomonas, aeruginosa, signaling, signalling, immunomodulator, Immunosuppressants, 6548, Tocris Bioscience

Citations for N-(3-Oxododecanoyl)-L-homoserine lactone

Citations are publications that use Tocris products.

Currently there are no citations for N-(3-Oxododecanoyl)-L-homoserine lactone.

Reviews for N-(3-Oxododecanoyl)-L-homoserine lactone

There are currently no reviews for this product. Be the first to review N-(3-Oxododecanoyl)-L-homoserine lactone and earn rewards!

Have you used N-(3-Oxododecanoyl)-L-homoserine lactone?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review