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Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC50 = 0.5 μM).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 50 mM in DMSO and to 5 mM in ethanol|
References are publications that support the biological activity of the product.
Hagiwara et al (1984) Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation. J.Pharmacol.Exp.Ther. 228 467 PMID: 6141286
Hidaka and Endo et al (1984) Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase, basic and potential clinical applications. Adv.Cyclic Nucleotide Protein Phosphorylation Res. 16 245 PMID: 6144253
If you know of a relevant reference for MY-5445, please let us know.
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Keywords: MY-5445, MY-5445 supplier, PDE5, inhibitors, inhibits, PDE, Phosphodiesterases, MY, 5445, 0432, Tocris Bioscience
Citations for MY-5445
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In vivo reproductive studies
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