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MRS 3777 hemioxalate
Discontinued ProductMRS 3777 hemioxalate (Cat. No. 2403) has been withdrawn from sale for commercial reasons.
Biological Activity for MRS 3777 hemioxalate
High affinity adenosine A3 receptor antagonist (Ki = 47 nM) that displays > 200-fold selectivity versus A1, A2A and A2B receptors.
Technical Data for MRS 3777 hemioxalate
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for MRS 3777 hemioxalate
References for MRS 3777 hemioxalate
References are publications that support the biological activity of the product.
Perreira et al (2005) "Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists. J.Med.Chem. 48 4910 PMID: 16033270
Jacobson and Gao (2006) Adenosine receptors as therapeutic targets. Nat.Rev.Drug Discov. 5 247 PMID: 16518376
Moro et al (2006) Progress in the pursuit of therapeutic adenosine receptor antagonists. Med.Res.Rev. 26 131 PMID: 16380972
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Keywords: MRS 3777 hemioxalate, MRS 3777 hemioxalate supplier, High, affinity, selective, A3, antagonists, Receptors, adenosines, MRS3777, hemioxalate, Adenosine, 2403, Tocris Bioscience
1 Citation for MRS 3777 hemioxalate
Citations are publications that use Tocris products. Selected citations for MRS 3777 hemioxalate include:
Schneider et al (2015) Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells. Nature 14 201 PMID: 26597723
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