Motilin (human, porcine)

Pricing Availability   Qty
Description: Endogenous peptide regulator of gastrointestinal motility
Purity: ≥95% (HPLC)
Citations (1)
Reviews (1)

Biological Activity for Motilin (human, porcine)

Motilin (human, porcine) is an endogenous motilin receptor ligand (Ki = 2.3 nM) that regulates gastrointestinal motor function. Stimulates contraction of gut smooth muscle (EC50 = 1 nM) and increases pepsin release.

Technical Data for Motilin (human, porcine)

M. Wt 2699.07
Formula C120H188N34O35S
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 52906-92-0
PubChem ID 16136567
Smiles [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Motilin (human, porcine)

Solubility Soluble to 1 mg/ml in water

Product Datasheets for Motilin (human, porcine)

Certificate of Analysis / Product Datasheet
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References for Motilin (human, porcine)

References are publications that support the biological activity of the product.

Itoh (1997) Motilin and clinical application. Peptides 18 593 PMID: 9210180

Coulie et al (2001) Identification of peptide ligand-binding domains within the human motilin receptor using photoaffinity labeling. J.Biol.Chem. 276 35518 PMID: 11461914

Huang et al (2005) Signaling pathways mediating gastrointestinal smooth muscle contraction and MLC20 phosphorylation by motilin receptors. Am.J.Physiol.Gastrointest.Liver Physiol. 288 G23 PMID: 15591586

If you know of a relevant reference for Motilin (human, porcine), please let us know.

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Keywords: Motilin (human, porcine), Motilin (human, porcine) supplier, Endogenous, peptide, regulator, gastrointestinal, motility, Motilin, Receptors, 2264, Tocris Bioscience

1 Citation for Motilin (human, porcine)

Citations are publications that use Tocris products. Selected citations for Motilin (human, porcine) include:

Broad and Sanger (2013) The antibiotic azithro. is a motilin receptor agonist in human stomach: comparison with erythro. Br J Pharmacol 168 1859 PMID: 23190027

Do you know of a great paper that uses Motilin (human, porcine) from Tocris? Please let us know.

Reviews for Motilin (human, porcine)

Average Rating: 5 (Based on 1 Review.)

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GI tissue bath.
By John Broad on 01/05/2018
Assay Type: In Vitro
Species: Human

Caused contraction of GI smooth muscle 10-300 nM

Soluble in H2O

PMID: 22537158
review image