MM 77 dihydrochloride

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Cat.No. 0933 - MM 77 dihydrochloride | C19H27N3O3.2HCl | CAS No. 159187-70-9
Description: 5-HT1A (postsynaptic) antagonist
Chemical Name: 1-(2-Methoxyphenyl)-4-(4-succinimidobutyl)piperazine dihydrochloride
Datasheet
Citations
Literature

Biological Activity

A highly potent and fairly selective 5-HT1A ligand, which may be a full antagonist at postsynaptic receptors.

Technical Data

M. Wt 418.36
Formula C19H27N3O3.2HCl
Storage Store at RT
CAS Number 159187-70-9
PubChem ID 45073441
InChI Key ZYCVVOZXHNDRCO-UHFFFAOYSA-N
Smiles Cl.Cl.COC1=CC=CC=C1N1CCN(CCCCN2C(=O)CCC2=O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.38 75

Preparing Stock Solutions

The following data is based on the product molecular weight 418.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.39 mL 11.95 mL 23.9 mL
5 mM 0.48 mL 2.39 mL 4.78 mL
10 mM 0.24 mL 1.2 mL 2.39 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

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Product Datasheets

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References

References are publications that support the products' biological activity.

Mokrosz et al (1994) 1-(2-Methoxyphenyl)-4-(4-succinimidobutyl)piperazine (MM 77): a new, potent, postsynaptic antagonist of 5-HT1A receptors. Med.Chem.Res. 4 161 PMID:


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Keywords: 5-HT1A postsynaptic antagonists Serotonin Receptors MM77 dihydrochloride 5-HT1A Receptors

Citations for MM 77 dihydrochloride

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Pathways for MM 77 dihydrochloride

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