Metaphit

Discontinued Product

Metaphit (Cat. No. 0568) has been withdrawn from sale for commercial reasons.
Cat.No. 0568 - Metaphit | C18H24N2S | CAS No. 96316-00-6
Description: Acylator of PCP and σ receptors
Chemical Name: 1-(1-(3-Isothiocyanato)phenyl)cyclohexylpiperidine
Datasheet
Citations
Reviews
Literature

Biological Activity

Acylator of PCP and σ-receptors.

Technical Data

M. Wt 300.46
Formula C18H24N2S
Storage Desiccate at -20°C
CAS Number 96316-00-6
PubChem ID 114745
InChI Key FGSGBQAQSPSRJK-UHFFFAOYSA-N
Smiles S=C=NC1=CC(=CC=C1)C1(CCCCC1)N1CCCCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

References

References are publications that support the biological activity of the product.

Contreras et al (1986) Metaphit, an acylating ligand for phencyclidine receptors: characterization of in vivo actions in the rat. J.Pharmacol.Exp.Ther. 238 1101 PMID: 3018219

Debler et al (1989) Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice. Eur.J.Pharmacol. 165 155 PMID: 2548879

Rafferty et al (1985) A specific acylating agent for the [3H]-phencyclidine receptors in rat brain. FEBS Lett. 181 318 PMID: 2982662

Reith et al (1991) Effect of metaphit on dopaminergic neurotransmission in rat striatal slices: involvement of the dopamine transporter and voltage-dependent sodium channel. J.Pharmacol.Exp.Ther. 259 1188 PMID: 1662274

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Keywords: Metaphit, Metaphit supplier, Acylator, PCP, σ, sigma, receptors, Sigma-Related, 0568, Tocris Bioscience

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Literature in this Area

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