Discontinued Product

Mephenytoin (Cat. No. 3276) has been withdrawn from sale for commercial reasons.
Description: CYP2C19 substrate. Anticonvulsant
Chemical Name: (±)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
Purity: ≥98% (HPLC)

Biological Activity for Mephenytoin

Mephenytoin is a CYP2C19 and CYP2B6 substrate. Anticonvulsant.

Technical Data for Mephenytoin

M. Wt 218.25
Formula C12H14N2O2
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 50-12-4
PubChem ID 4060
Smiles O=C1C(C2=CC=CC=C2)(CC)NC(N1C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for Mephenytoin

References are publications that support the biological activity of the product.

Knabe and Wunn (1980) Racemic and optically active hydantoins from disubstituted cyanoacetic acids. Arch.Pharmacol. 313 53

Foti et al (2008) CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles. Drug Meta. Dispos. 36 523 PMID: 18048485

Tamminga et al (2001) Mephenytoin as a probe for CYP2C19 phenotyping: effect of sample storage, intra-individual reproducibility and occurrence of adverse events. Br.J.Clin.Pharmacol. 51 471 PMID: 11422005

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Keywords: Mephenytoin, Mephenytoin supplier, CYP2C19, Anticonvulsant, Cytochrome, P450, 3276, Tocris Bioscience

Citations for Mephenytoin

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Currently there are no citations for Mephenytoin.

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