You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
MDL 72832 hydrochloride
A potent ligand at 5-HT1A receptors, with mixed agonist and antagonist properties. An agonist at post-synaptic 5-HT1A receptors.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 422.95. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.05 mM||47.29 mL||236.43 mL||472.87 mL|
|0.25 mM||9.46 mL||47.29 mL||94.57 mL|
|0.5 mM||4.73 mL||23.64 mL||47.29 mL|
|2.5 mM||0.95 mL||4.73 mL||9.46 mL|
References are publications that support the biological activity of the product.
Millan et al (1993) Induction of hypothermia as a model of 5-hydroxytryptamine1A receptor-mediated activity in the rat - a pharmacological characterization of the actions of novel agonists and antagonists. J.Pharmacol.Exp.Ther. 264 1364 PMID: 8450471
Mir et al (1988) MDL 72832: a potent and stereoselective ligand at central and peripheral 5-HT1A receptors. Eur.J.Pharmacol. 149 107 PMID: 2840295
If you know of a relevant reference for MDL 72832 hydrochloride, please let us know.
View Related Products by Product Action
Keywords: MDL 72832 hydrochloride, MDL 72832 hydrochloride supplier, Potent, 5-HT1A, ligand, Serotonin, Receptors, 5-HT1, MDL72832, hydrochloride, 0412, Tocris Bioscience
Citations for MDL 72832 hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for MDL 72832 hydrochloride. Do you know of a great paper that uses MDL 72832 hydrochloride from Tocris? Please let us know.
Reviews for MDL 72832 hydrochloride
There are currently no reviews for this product. Be the first to review MDL 72832 hydrochloride and earn rewards!
Have you used MDL 72832 hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.