Discontinued ProductUnfortunately MBCQ (Cat. No. 0874) has been withdrawn from sale for commercial reasons.
Very selective inhibitor of cGMP-specific phosphodiesterase (PDE5) (IC50 = 0.019 μM).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 313.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.19 mL||15.94 mL||31.87 mL|
|5 mM||0.64 mL||3.19 mL||6.37 mL|
|10 mM||0.32 mL||1.59 mL||3.19 mL|
|50 mM||0.06 mL||0.32 mL||0.64 mL|
References are publications that support the products' biological activity.
Sampson et al (2001) Evidence for expression and function of phosphodiesterase type 5 (PDE-V) in rat resistance arteries. Br.J.Pharmacol. 132 13 PMID: 11156556
Takase et al (1994) Cyclic GMP phosphodiesterase inhibitors. 2. Requirement of 6-subsitution of quinazoline derivatives for potent and selective inhibitory activity. J.Med.Chem. 37 2106 PMID: 8027992
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Keywords: MBCQ, supplier, Phosphodiesterases, Phosphodiesterases, Tocris Bioscience
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