Discontinued Product

MBCQ (Cat. No. 0874) has been withdrawn from sale for commercial reasons.
Description: PDE5 inhibitor
Chemical Name: 4-[[3,4-(Methylenedioxy)benzyl]amino]-6-chloroquinazoline
Literature (1)

Biological Activity for MBCQ

Very selective inhibitor of cGMP-specific phosphodiesterase (PDE5) (IC50 = 0.019 μM).

Technical Data for MBCQ

M. Wt 313.74
Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for MBCQ

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for MBCQ

References are publications that support the biological activity of the product.

Sampson et al (2001) Evidence for expression and function of phosphodiesterase type 5 (PDE-V) in rat resistance arteries. Br.J.Pharmacol. 132 13 PMID: 11156556

Takase et al (1994) Cyclic GMP phosphodiesterase inhibitors. 2. Requirement of 6-subsitution of quinazoline derivatives for potent and selective inhibitory activity. J.Med.Chem. 37 2106 PMID: 8027992

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Keywords: MBCQ, MBCQ supplier, Phosphodiesterases, 0874, Tocris Bioscience

Citations for MBCQ

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Currently there are no citations for MBCQ.

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Literature in this Area

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Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

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