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Description: PDE5 inhibitor
Chemical Name: 4-[[3,4-(Methylenedioxy)benzyl]amino]-6-chloroquinazoline
Biological Activity for MBCQ
Very selective inhibitor of cGMP-specific phosphodiesterase (PDE5) (IC50 = 0.019 μM).
Technical Data for MBCQ
| M. Wt | 313.74 |
| Storage | Store at RT |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for MBCQ
Certificate of Analysis is currently unavailable on-line.
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References for MBCQ
References are publications that support the biological activity of the product.
Sampson et al (2001) Evidence for expression and function of phosphodiesterase type 5 (PDE-V) in rat resistance arteries. Br.J.Pharmacol. 132 13 PMID: 11156556
Takase et al (1994) Cyclic GMP phosphodiesterase inhibitors. 2. Requirement of 6-subsitution of quinazoline derivatives for potent and selective inhibitory activity. J.Med.Chem. 37 2106 PMID: 8027992
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Keywords: MBCQ, MBCQ supplier, Phosphodiesterases, 0874, Tocris Bioscience
Citations for MBCQ
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