Discontinued Product

Mastoparan (Cat. No. 1192) has been withdrawn from sale for commercial reasons.
Description: Activates Gi and Go
Citations (1)

Biological Activity for Mastoparan

Mastoparan is a peptide activator of Gi and Go.

Technical Data for Mastoparan

M. Wt 1479
Formula C70H131N19O15

(Modifications: Leu-14 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 72093-21-1
PubChem ID 6324633
Smiles [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Mastoparan

Certificate of Analysis / Product Datasheet
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References for Mastoparan

References are publications that support the biological activity of the product.

Higashijima and Ros (1991) Mapping of the mastoparan-binding site on G proteins. Cross-linking of [125I-Tyr3,Cys11]mastoparan to Go. J.Biol.Chem. 266 12655 PMID: 1905730

Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799 PMID: 10329678

Mousli et al (1990) G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. TiPS 11 358 PMID: 2122563

Raynor et al (1991) Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin. J.Biol.Chem. 266 2753 PMID: 1847132

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Keywords: Mastoparan, Mastoparan supplier, Activator, Gi, Go, Gi/o, G-Protein, Signaling, Signalling, Heterotrimeric, G-protein, GTPases, 1192, Tocris Bioscience

1 Citation for Mastoparan

Citations are publications that use Tocris products. Selected citations for Mastoparan include:

Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888

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