Mastoparan X

Discontinued Product

Mastoparan X (Cat. No. 1896) has been withdrawn from sale for commercial reasons.
Cat.No. 1896 - Mastoparan X | Ile-Asn-Trp-Lys-Gly-Ile-Ala-Ala-Met-Ala-Lys-Lys-Leu-Leu-NH2 | CAS No. 72093-22-2
Description: G protein activator peptide
Datasheet
Citations
Reviews
Literature

Biological Activity

Amphiphilic G protein activator peptide that binds to Gi and Go. Also binds with high affinity to calmodulin (Kd ~ 0.9 nM) and inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki = 4.4 mM).

Technical Data

M. Wt 1555.98
Formula C73H126N20O15S
Sequence INWKGIAAMAKKLL

(Modifications: Leu-14 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 72093-22-2
Smiles [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Safety Datasheet

References

References are publications that support the biological activity of the product.

Higashijima et al (1990) Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. J.Biol.Chem. 265 14176 PMID: 2117607

Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799 PMID: 10329678

Sukumar and Higashijima (1992) G protein-bound conformation of mastoparan-X, a receptor-mimetic peptide. J.Biol.Chem. 267 21421 PMID: 1400455

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Keywords: Mastoparan X, Mastoparan X supplier, G, protein, activators, peptide, Gi, Go, Heterotrimeric, MastoparanX, Protein, (Heterotrimeric), 1896, Tocris Bioscience

Citations for Mastoparan X

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