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Mastoparan-7

Cat. No. 1895 Submit a Review Datasheet / COA / SDS

Discontinued Product

Mastoparan-7 (Cat. No. 1895) has been withdrawn from sale for commercial reasons.
Cat.No. 1895 - Mastoparan -7 | CAS No. 145854-59-7
Description: G protein activator peptide
Alternative Names: Mas 7
Datasheet
Citations
Reviews
Literature
Biological Activity Technical Data Datasheets References

Biological Activity

Amphiphilic G protein activator peptide that forms a-helices in lipid membranes; more potent and efficacious than mastoparan (Cat. No. 1192). Inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki = 2.2 mM). Also induces cation-permeable pore formation and Ca2+ influx in SK-N-BE(2)C cells.

Technical Data

M. Wt 1421.83
Formula C67H124N18O15
Storage Desiccate at -20°C
CAS Number 145854-59-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References

References are publications that support the biological activity of the product.

Higashijima et al (1990) Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. J.Biol.Chem. 265 14176 PMID: 2117607

Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799 PMID: 10329678

Suh et al (1996) Induction of cytosolic Ca2+ elevation mediated by Mas-7 occurs through membrane pore formation. J.Biol.Chem. 271 32753 PMID: 8955110

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Keywords: Mastoparan -7, Mastoparan -7 supplier, Amphiphilic, G, protein, activator, peptide, that, forms, a-helices, in, lipid, membranes;, more, potent, and, efficacious, than, mastoparan, (Cat., No., 1192)., Inhibits, sarcoplasmic, reticulum, Ca2+-ATPase, (Ki, =, 2.2, mM)., Also, induces, cation-permeable, pore, formation, Ca2+, infl, Mas, 7, Heterotrimeric, G-protein, GTPases, 1895, Tocris Bioscience

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