Discontinued Product

Unfortunately Mastoparan-7 (Cat. No. 1895) has been withdrawn from sale for commercial reasons.
Cat.No. 1895 - Mastoparan -7 | CAS No. 145854-59-7
Description: G protein activator peptide
Alternative Names: Mas 7

Biological Activity

Amphiphilic G protein activator peptide that forms a-helices in lipid membranes; more potent and efficacious than mastoparan (Cat. No. 1192). Inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki = 2.2 mM). Also induces cation-permeable pore formation and Ca2+ influx in SK-N-BE(2)C cells.

Technical Data

M. Wt 1421.83
Formula C67H124N18O15
Storage Desiccate at -20°C
CAS Number 145854-59-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 1421.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.7 mL 3.52 mL 7.03 mL
5 mM 0.14 mL 0.7 mL 1.41 mL
10 mM 0.07 mL 0.35 mL 0.7 mL
50 mM 0.01 mL 0.07 mL 0.14 mL

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Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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Safety Datasheet


References are publications that support the products' biological activity.

Higashijima et al (1990) Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. J.Biol.Chem. 265 14176 PMID: 2117607

Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799 PMID: 10329678

Suh et al (1996) Induction of cytosolic Ca2+ elevation mediated by Mas-7 occurs through membrane pore formation. J.Biol.Chem. 271 32753 PMID: 8955110

View Related Products by Target

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