Discontinued ProductUnfortunately Mastoparan-7 (Cat. No. 1895) has been withdrawn from sale for commercial reasons.
Amphiphilic G protein activator peptide that forms a-helices in lipid membranes; more potent and efficacious than mastoparan (Cat. No. 1192). Inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki = 2.2 mM). Also induces cation-permeable pore formation and Ca2+ influx in SK-N-BE(2)C cells.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 1421.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.7 mL||3.52 mL||7.03 mL|
|5 mM||0.14 mL||0.7 mL||1.41 mL|
|10 mM||0.07 mL||0.35 mL||0.7 mL|
|50 mM||0.01 mL||0.07 mL||0.14 mL|
References are publications that support the products' biological activity.
Higashijima et al (1990) Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. J.Biol.Chem. 265 14176 PMID: 2117607
Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799 PMID: 10329678
Suh et al (1996) Induction of cytosolic Ca2+ elevation mediated by Mas-7 occurs through membrane pore formation. J.Biol.Chem. 271 32753 PMID: 8955110
Keywords: Mastoparan -7, supplier, Amphiphilic, G, protein, activator, peptide, that, forms, a-helices, in, lipid, membranes;, more, potent, and, efficacious, than, mastoparan, (Cat., No., 1192)., Inhibits, sarcoplasmic, reticulum, Ca2+-ATPase, (Ki, =, 2.2, mM)., Also, induces, cation-permeable, pore, formation, Ca2+, infl, Mas, 7, G, Protein, (Heterotrimeric), G, Protein, (Heterotrimeric), Tocris Bioscience
Citations for Mastoparan-7
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Currently there are no citations for Mastoparan-7.
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