Discontinued ProductMastoparan-7 (Cat. No. 1895) has been withdrawn from sale for commercial reasons.
Amphiphilic G protein activator peptide that forms a-helices in lipid membranes; more potent and efficacious than mastoparan (Cat. No. 1192). Inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki = 2.2 mM). Also induces cation-permeable pore formation and Ca2+ influx in SK-N-BE(2)C cells.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
References are publications that support the biological activity of the product.
Higashijima et al (1990) Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. J.Biol.Chem. 265 14176 PMID: 2117607
Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799 PMID: 10329678
Suh et al (1996) Induction of cytosolic Ca2+ elevation mediated by Mas-7 occurs through membrane pore formation. J.Biol.Chem. 271 32753 PMID: 8955110
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Keywords: Mastoparan -7, Mastoparan -7 supplier, Amphiphilic, G, protein, activator, peptide, that, forms, a-helices, in, lipid, membranes;, more, potent, and, efficacious, than, mastoparan, (Cat., No., 1192)., Inhibits, sarcoplasmic, reticulum, Ca2+-ATPase, (Ki, =, 2.2, mM)., Also, induces, cation-permeable, pore, formation, Ca2+, infl, Mas, 7, Protein, (Heterotrimeric), 1895, Tocris Bioscience
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