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Biological Activity for MAFP
Potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH, anandamide amidase), the enzyme responsible for anandamide hydrolysis (IC50 = 2.5 nM). Also binds irreversibly to CB1 receptors (IC50 = 20 nM).
Technical Data for MAFP
|Storage||Desiccate at -80°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for MAFP
References are publications that support the biological activity of the product.
De Petrocellis et al (1997) Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase. Biochem.Biophys.Res.Commun. 231 82 PMID: 9070224
Deutsch et al (1997) Methyl arachidonyl fluorophosphate: a potent irreversible inhibitor of anandamide amidase. Biochem.Pharmacol. 53 255 PMID: 9065728
Martin et al (2000) Cannabinoid properties of methylfluorophosphonate analogs. J.Pharmacol.Exp.Ther. 294 1209 PMID: 10945879
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Keywords: MAFP, MAFP supplier, Potent, irreversible, FAAH, inhibitors, inhibits, Anandamide, Amidase, Fatty, Acid, Amide, Hydrolases, Cannabinoids, Receptors, Other, Hydrolase, (FAAH), 1421, Tocris Bioscience
Citations for MAFP
Citations are publications that use Tocris products.
Currently there are no citations for MAFP.
Reviews for MAFP
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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