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Discontinued Product
M-6434 (Cat. No. 0461) has been withdrawn from sale for commercial reasons.
Description: a1 agonist
Chemical Name: 2-[(5-Chloro-2-methoxyphenyl)azo]-1H-imidazole
Biological Activity for M-6434
An α1-agonist; a potent orally active hypertensive.
Technical Data for M-6434
| M. Wt | 236.66 |
| Formula | C10H9CIN4O |
| Storage | Store at RT |
| CAS Number | 77636-92-1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for M-6434
Certificate of Analysis is currently unavailable on-line.
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References for M-6434
References are publications that support the biological activity of the product.
Dabasaki et al (1992) Antihypotensive effects of M6434, an orally active alpha-1-adrenoceptor agonist in rats. Jpn.J.Pharmacol. 59 145 PMID: 1279249
Ohnish (1981) Pharmacological properties of 2-[(5-chloro-2-methoxyphenyl)azo]-1H-imidazole (M6434). Arzneimittelforschung 9 1425 PMID: 7197948
Tsuchid (1986) Effects of mido. on experimentally-induced postural hypotension in dogs. Arzneimittelforschung 12 1748 PMID: 2436631
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Keywords: M-6434, M-6434 supplier, An, a1-agonist;, a, potent, orally, active, hypertensive., Adrenergic, Alpha-1, Receptors, 0461, Tocris Bioscience
Citations for M-6434
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Currently there are no citations for M-6434.
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Literature in this Area
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Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.