Potent and selective galanin receptor 2 (GAL2) agonist (EC50 = 38 nM, Ki values are 6.55, 497 and 587 nM at GAL2, GAL3 and GAL1 respectively). Has an additive effect on the signal transduction of galanin.
(Modifications: Ala-27 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 5 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 2774.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.36 mL||1.8 mL||3.6 mL|
|5 mM||0.07 mL||0.36 mL||0.72 mL|
|10 mM||0.04 mL||0.18 mL||0.36 mL|
|50 mM||0.01 mL||0.04 mL||0.07 mL|
References are publications that support the biological activity of the product.
Runesson et al (2009) A novel GalR2-specific peptide agonist. Neuropeptides 43 187 PMID: 19467704
If you know of a relevant reference for M 1145, please let us know.
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Keywords: M 1145, M 1145 supplier, Potent, selective, GAL2, GalR2, agonists, Receptors, Galanin, M1145, 3629, Tocris Bioscience
Citations for M 1145
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.