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Potent and selective galanin receptor 2 (GAL2) agonist (EC50 = 38 nM, Ki values are 6.55, 497 and 587 nM at GAL2, GAL3 and GAL1 respectively). Has an additive effect on the signal transduction of galanin.
(Modifications: Ala-27 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 5 mg/ml in water|
References are publications that support the biological activity of the product.
Runesson et al (2009) A novel GalR2-specific peptide agonist. Neuropeptides 43 187 PMID: 19467704
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Keywords: M 1145, M 1145 supplier, Potent, selective, GAL2, GalR2, agonists, Receptors, Galanin, M1145, 3629, Tocris Bioscience
1 Citation for M 1145
Citations are publications that use Tocris products. Selected citations for M 1145 include:
Fang (2018) Central galanin receptor 2 mediates galanin action to promote systemic glucose metabolism of type 2 diabetic rats. Biochem Pharmacol 156 241 PMID: 30170096
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.