Antioxidant; protects against ischemia-induced neuronal damage in rat models of global and focal cerebral ischemia. Neuroprotective in vitro and in vivo.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 299.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.33 mL||16.67 mL||33.35 mL|
|5 mM||0.67 mL||3.33 mL||6.67 mL|
|10 mM||0.33 mL||1.67 mL||3.33 mL|
|50 mM||0.07 mL||0.33 mL||0.67 mL|
References are publications that support the biological activity of the product.
Clemens et al (1993) The antioxidant LY 231617 reduces global ischemic neuronal injury in rats. Stroke 24 716 PMID: 8488528
Fuson et al (1999) Characterization of LY 231617 protection against hydrogen peroxide toxicity. J.Neurochem. 72 1154 PMID: 10037488
O'Neill et al (1997) Neuroprotective effects of the antioxidant LY 231617 and NO synthase inhibitors in global ischaemia. Brain Res. 760 170 PMID: 9237532
If you know of a relevant reference for LY 231617, please let us know.
View Related Products by Target
Keywords: LY 231617, LY 231617 supplier, LY231617, antioxidants, anti-oxidants, neuroprotective, ischaemia-induced, neuronal, damage, global, cerebral, ischemia, Antioxidants, 1286, Tocris Bioscience
Citations for LY 231617
Citations are publications that use Tocris products.
Currently there are no citations for LY 231617. Do you know of a great paper that uses LY 231617 from Tocris? Please let us know.
Reviews for LY 231617
There are currently no reviews for this product. Be the first to review LY 231617 and earn rewards!
Have you used LY 231617?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Spring/Summer 2018)
Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Cell Metabolism
- Fluorescent Imaging
- Signal Transduction
- Stem Cells