LRGILS-NH2

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Cat.No. 3394 - LRGILS-NH2 | Leu-Arg-Gly-Ile-Leu-Ser-NH2 | CAS No. 245329-01-5
Description: Control peptide for SLIGRL-NH2 (Cat. No. 1468)
Datasheet
Citations
Literature

Biological Activity

Reversed amino acid sequence control peptide for SLIGRL-NH2 (Cat. No. 1468), a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo.

Technical Data

M. Wt 656.83
Formula C29H56N10O7
Sequence LRGILS

(Modifications: Ser-6 = C-terminal amide)

Storage Store at -20°C
CAS Number 245329-01-5
PubChem ID 90488840
InChI Key HCUFWKYFOMBFPA-JYAZKYGWSA-N
Smiles [H]N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 2 mg/ml in 30% acetonitrile / water

Preparing Stock Solutions

The following data is based on the product molecular weight 656.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.52 mL 7.61 mL 15.22 mL
5 mM 0.3 mL 1.52 mL 3.04 mL
10 mM 0.15 mL 0.76 mL 1.52 mL
50 mM 0.03 mL 0.15 mL 0.3 mL

Molarity Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Tognetto et al (2000) Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder. Br.J.Pharmacol. 131 689 PMID: 11030717

Nishikawa et al (2005) Protease-activated receptor-2 (PAR-2)-related peptides induce tear secretion in Rats: Involvement of PAR-2 and non-PAR-2 mechanisms. J.Pharmacol.Exp.Ther. 312 324 PMID: 15331653

Devlin et al (2007) Initial support for the hypothesis that PAR2 is involved in the immune response to Nippostrongylus brasiliensis in mice. Parasitol.Res. 101 105 PMID: 17458579


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Keywords: Control peptide SLIGRL-NH2 PAR Receptors Protease-Activated proteinase-activated Protease-Activated Receptors

Citations for LRGILS-NH2

Citations are publications that use Tocris products.

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Literature in this Area

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Pathways for LRGILS-NH2

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