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Description: Control peptide for SLIGRL-NH2 (Cat. No. 1468)
Purity: ≥95% (HPLC)
Reviews (1)

Biological Activity for LRGILS-NH2

LRGILS-NH2 is a reversed amino acid sequence control peptide for SLIGRL-NH2, a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo.

Active Analog also available.

Technical Data for LRGILS-NH2

M. Wt 656.83
Formula C29H56N10O7
Sequence LRGILS

(Modifications: Ser-6 = C-terminal amide)

Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 245329-01-5
PubChem ID 90488840
Smiles [H]N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for LRGILS-NH2

Solubility Soluble to 2 mg/ml in water

Product Datasheets for LRGILS-NH2

Certificate of Analysis / Product Datasheet
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References for LRGILS-NH2

References are publications that support the biological activity of the product.

Tognetto et al (2000) Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder. Br.J.Pharmacol. 131 689 PMID: 11030717

Nishikawa et al (2005) Protease-activated receptor-2 (PAR-2)-related peptides induce tear secretion in Rats: Involvement of PAR-2 and non-PAR-2 mechanisms. J.Pharmacol.Exp.Ther. 312 324 PMID: 15331653

Devlin et al (2007) Initial support for the hypothesis that PAR2 is involved in the immune response to Nippostrongylus brasiliensis in mice. Parasitol.Res. 101 105 PMID: 17458579

If you know of a relevant reference for LRGILS-NH2, please let us know.

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Keywords: LRGILS-NH2, LRGILS-NH2 supplier, Control, peptide, SLIGRL-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, 3394, Tocris Bioscience

Citations for LRGILS-NH2

Citations are publications that use Tocris products.

Currently there are no citations for LRGILS-NH2. Do you know of a great paper that uses LRGILS-NH2 from Tocris? Please let us know.

Reviews for LRGILS-NH2

Average Rating: 4 (Based on 1 Review.)

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Good and easy product to use for regular in-vitro stimulations.
By Anonymous on 11/20/2019
Assay Type: In Vitro
Species: Human
Cell Line/Tissue: Smooth Muscle Cells

Was used in an in-vitro stimulation assay as a control peptide