Reversed amino acid sequence control peptide for SLIGRL-NH2, a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo.
Active Analog also available.
(Modifications: Ser-6 = C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 2 mg/ml in 30% acetonitrile / water|
Preparing Stock Solutions
The following data is based on the product molecular weight 656.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.52 mL||7.61 mL||15.22 mL|
|5 mM||0.3 mL||1.52 mL||3.04 mL|
|10 mM||0.15 mL||0.76 mL||1.52 mL|
|50 mM||0.03 mL||0.15 mL||0.3 mL|
References are publications that support the biological activity of the product.
Tognetto et al (2000) Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder. Br.J.Pharmacol. 131 689 PMID: 11030717
Nishikawa et al (2005) Protease-activated receptor-2 (PAR-2)-related peptides induce tear secretion in Rats: Involvement of PAR-2 and non-PAR-2 mechanisms. J.Pharmacol.Exp.Ther. 312 324 PMID: 15331653
Devlin et al (2007) Initial support for the hypothesis that PAR2 is involved in the immune response to Nippostrongylus brasiliensis in mice. Parasitol.Res. 101 105 PMID: 17458579
If you know of a relevant reference for LRGILS-NH2, please let us know.
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Keywords: LRGILS-NH2, LRGILS-NH2 supplier, Control, peptide, SLIGRL-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, 3394, Tocris Bioscience
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