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Litorin is an amphibian bombesin-like peptide. Stimulates smooth muscle contraction, gastrin release, gastric acid and pancreatic secretion, and suppresses food intake in vivo.
(Modifications: X = Glp, Met-9 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Endean et al (1975) Parallel bioassay of bombesin and litorin, a bombesin-like peptide from the skin of Litoria aurea. Br.J.Pharmacol. 55 213 PMID: 1201379
Kulkosky and Gibbs (1982) Litorin suppresses food intake in rats. Life Sci. 31 685 PMID: 6290821
Lin et al (1995) Comparison of the peptide structural requirements for high affinity interaction with bombesin receptors. Eur.J.Pharmacol. 294 55 PMID: 8788416
Keywords: Litorin, Litorin supplier, Amphibian, bombesin-like, peptide, GRP-Preferring, Receptors, BB1-3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, 1916, Tocris Bioscience
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.