Levonorgestrel

Pricing Availability Delivery Time Qty
Cat.No. 4833 - Levonorgestrel | C21H28O2 | CAS No. 797-63-7
Description: Synthetic progesterone analog
Chemical Name: (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-yn-3-one
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Synthetic progesterone analog; binds to the progesterone receptor (relative binding affinities are < 0.02, 7.5, 17, 58 and 323 % for estrogen receptors, glucocorticoid receptors, mineralocorticoid receptors, androgen receptors and progesterone receptors respectively).

Compound Libraries

Levonorgestrel is also offered as part of the Tocriscreen Plus and Tocriscreen Library of FDA-Approved Compounds. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 312.45
Formula C21H28O2
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 797-63-7
PubChem ID 13109
InChI Key WWYNJERNGUHSAO-XUDSTZEESA-N
Smiles [H][C@@]12C(CC[C@]3([H])[C@@]([H])2CC[C@@]4(CC)[C@]([H])3CC[C@@](C#C)4O)=CC(CC1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.25 100

Preparing Stock Solutions

The following data is based on the product molecular weight 312.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.2 mL 16 mL 32.01 mL
5 mM 0.64 mL 3.2 mL 6.4 mL
10 mM 0.32 mL 1.6 mL 3.2 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Sitruk-Ware et al (2006) New progestagens for contraceptive use. Hum.Reprod.Update 12 169 PMID: 16291771


If you know of a relevant reference for Levonorgestrel, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Progesterone Receptor Agonists

Keywords: synthetic progesterone receptors progestin progestogen analogs contraceptives Progesterone Receptor

Citations for Levonorgestrel

Citations are publications that use Tocris products.

Currently there are no citations for Levonorgestrel. Do you know of a great paper that uses Levonorgestrel from Tocris? If so please let us know.

Commented out for usability testing

Reviews

TODO: Add Reviews

Literature in this Area

Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Nuclear Receptors

Nuclear Receptors Product Listing

A collection of over 150 products for key nuclear receptors, the listing includes research tools for the study of:

  • Androgen Receptors
  • Estrogen Receptors
  • Retinoic Acid Receptors
  • Retinoid X Receptors
  • Vitamin D Receptors

Pathways for Levonorgestrel

Protocols

TODO: Add Protocols