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Cat.No. 4833 - Levonorgestrel | C21H28O2 | CAS No. 797-63-7
Description: Synthetic progesterone analog
Chemical Name: (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-yn-3-one
Purity: ≥98% (HPLC)

Biological Activity

Synthetic progesterone analog; binds to the progesterone receptor (relative binding affinities are < 0.02, 7.5, 17, 58 and 323 % for estrogen receptors, glucocorticoid receptors, mineralocorticoid receptors, androgen receptors and progesterone receptors respectively).

Compound Libraries

Levonorgestrel is also offered as part of the Tocriscreen Plus and Tocriscreen Library of FDA-Approved Compounds. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 312.45
Formula C21H28O2
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 797-63-7
PubChem ID 13109
Smiles [H][C@@]12C(CC[C@]3([H])[C@@]([H])2CC[C@@]4(CC)[C@]([H])3CC[C@@](C#C)4O)=CC(CC1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 31.25 100

Preparing Stock Solutions

The following data is based on the product molecular weight 312.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.2 mL 16 mL 32.01 mL
5 mM 0.64 mL 3.2 mL 6.4 mL
10 mM 0.32 mL 1.6 mL 3.2 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Sitruk-Ware et al (2006) New progestagens for contraceptive use. Hum.Reprod.Update 12 169 PMID: 16291771

If you know of a relevant reference for Levonorgestrel, please let us know.

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Keywords: synthetic progesterone receptors progestin progestogen analogs contraceptives Progesterone Receptor

Citations for Levonorgestrel

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Literature in this Area


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Pathways for Levonorgestrel


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