Levonorgestrel

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Cat.No. 4833 - Levonorgestrel | C21H28O2 | CAS No. 797-63-7
Description: Synthetic progesterone analog
Chemical Name: (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-yn-3-one
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Synthetic progesterone analog; binds to the progesterone receptor (relative binding affinities are < 0.02, 7.5, 17, 58 and 323 % for estrogen receptors, glucocorticoid receptors, mineralocorticoid receptors, androgen receptors and progesterone receptors respectively).

Compound Libraries

Levonorgestrel is also offered as part of the Tocriscreen Plus and Tocriscreen Library of FDA-Approved Compounds. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 312.45
Formula C21H28O2
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 797-63-7
PubChem ID 13109
InChI Key WWYNJERNGUHSAO-XUDSTZEESA-N
Smiles [H][C@@]12C(CC[C@]3([H])[C@@]([H])2CC[C@@]4(CC)[C@]([H])3CC[C@@](C#C)4O)=CC(CC1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.25 100

Preparing Stock Solutions

The following data is based on the product molecular weight 312.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.2 mL 16 mL 32.01 mL
5 mM 0.64 mL 3.2 mL 6.4 mL
10 mM 0.32 mL 1.6 mL 3.2 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the biological activity of the product.

Sitruk-Ware et al (2006) New progestagens for contraceptive use. Hum.Reprod.Update 12 169 PMID: 16291771


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Keywords: Levonorgestrel, Levonorgestrel supplier, synthetic, progesterone, receptors, progestin, progestogen, analogs, contraceptives, Progesterone, Receptor, 4833, Tocris Bioscience

Citations for Levonorgestrel

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