Leuprolide

Pricing Availability   Qty
Cat.No. 2873 - Leuprolide | Glp-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt | CAS No. 53714-56-0
Description: GnRH receptor agonist
Alternative Names: Leuoprorelin
Datasheet
Citations
Reviews
Literature

Biological Activity

Gonadotropin-releasing hormone (GnRH, luteinizing hormone-releasing hormone, LHRH) receptor agonist. Suppresses estradiol, LH and FSH serum levels and represses the growth of experimental rat endometriosis.

Technical Data

M. Wt 1209.41
Formula C59H84N16O12
Sequence XHWSYLLRP

(Modifications: X1 = Glp, Pro-9 = Pro-NHEt)

Storage Desiccate at -20°C
CAS Number 53714-56-0
PubChem ID 90488782
InChI Key GFIJNRVAKGFPGQ-UILVTTEASA-N
Smiles [H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 0.50 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Okada et al (1988) One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. J.Pharmacol.Exp.Ther. 244 744 PMID: 3126294

Uday et al (2007) LHRH antagonist attenuates the effect of fluox. on marble-burying behavior in mice. Eur.J.Pharmacol. 563 155 PMID: 17368614

Salvador et al (2001) Effects of the luteinising hormone-releasing hormone (LH-RH) agonist leupr. on adenylyl cyclase regulation through G-protein coupled receptors in rat ventral prostate. Eur.J.Pharmacol. 37 641


If you know of a relevant reference for Leuprolide, please let us know.

View Related Products by Product Action

View all Gonadotropin-Releasing Hormone Receptor Agonists

Keywords: Leuprolide, Leuprolide supplier, GnRH, receptor, agonists, Receptors, Gonadotrophin-Releasing, Hormone, gonadotropin, chemotherapeutics, Leuoprorelin, 2873, Tocris Bioscience

Citations for Leuprolide

Citations are publications that use Tocris products.

Currently there are no citations for Leuprolide. Do you know of a great paper that uses Leuprolide from Tocris? Please let us know.

Reviews for Leuprolide

There are currently no reviews for this product. Be the first to review Leuprolide and earn rewards!

Have you used Leuprolide?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Peptide Hormone Receptors

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing