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Gonadotropin-releasing hormone (GnRH, luteinizing hormone-releasing hormone, LHRH) receptor agonist. Suppresses estradiol, LH and FSH serum levels and represses the growth of experimental rat endometriosis.
(Modifications: X1 = Glp, Pro-9 = Pro-NHEt)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 0.50 mg/ml in water|
References are publications that support the biological activity of the product.
Okada et al (1988) One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. J.Pharmacol.Exp.Ther. 244 744 PMID: 3126294
Uday et al (2007) LHRH antagonist attenuates the effect of fluox. on marble-burying behavior in mice. Eur.J.Pharmacol. 563 155 PMID: 17368614
Salvador et al (2001) Effects of the luteinising hormone-releasing hormone (LH-RH) agonist leupr. on adenylyl cyclase regulation through G-protein coupled receptors in rat ventral prostate. Eur.J.Pharmacol. 37 641
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Keywords: Leuprolide, Leuprolide supplier, GnRH, receptor, agonists, Receptors, Gonadotrophin-Releasing, Hormone, gonadotropin, chemotherapeutics, Leuoprorelin, 2873, Tocris Bioscience
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