LEP (116-130) (mouse)

Pricing Availability   Qty
Cat.No. 2985 - LEP (116-130) (mouse) | Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2 | CAS No. 258276-95-8
Description: Synthetic leptin peptide fragment
Datasheet
Citations
Reviews
Literature

Biological Activity

Synthetic leptin peptide fragment. Restricts weight gain and reduces food intake in female mice lacking endogenously circulating active leptin.

Technical Data

M. Wt 1560.73
Formula C64H109N19O24S
Sequence SCSLPQTSGLQKPES

(Modifications: Ser-15 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 258276-95-8
PubChem ID 90471193
InChI Key YEHDWBRMEXDYLT-RDEOYNLOSA-N
Smiles [H]N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Grasso et al (1997) In vivo effects of leptin-related synthetic peptides on body weight and food intake in female ob/ob mice: localization of leptin activity to domains between amino acid residues 106-140. Endocrinology 138 1413 PMID: 9075696

Grasso et al (1999) Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor. Diabetes 48 2204 PMID: 10535455

Rozhavskaya et al (2000) Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis and thermoregulation. Endocrinology 141 2501 PMID: 10875251


If you know of a relevant reference for LEP (116-130) (mouse), please let us know.

View Related Products by Target

Keywords: LEP (116-130) (mouse), LEP (116-130) (mouse) supplier, Synthetic, leptin, peptide, fragment, Receptors, adipokines, Leptin, 2985, Tocris Bioscience

Citations for LEP (116-130) (mouse)

Citations are publications that use Tocris products.

Currently there are no citations for LEP (116-130) (mouse). Do you know of a great paper that uses LEP (116-130) (mouse) from Tocris? Please let us know.

Reviews for LEP (116-130) (mouse)

There are currently no reviews for this product. Be the first to review LEP (116-130) (mouse) and earn rewards!

Have you used LEP (116-130) (mouse)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Peptides Involved in Appetite Modulation

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.