Discontinued Product

Latanoprost (Cat. No. 4757) has been withdrawn from sale for commercial reasons.
Description: FP prostaglandin receptor agonist; also exhibits agonist activity at EP1 and EP3 receptors
Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptanoic acid 1-methylethyl ester
Purity: ≥97% (HPLC)

Biological Activity for Latanoprost

Latanoprost is a FP prostaglandin receptor agonist; displays greater selectivity than prostanglandin F2α (Cat. No. 4214). Exhibits agonist activity at EP1 and EP3 receptors, but little-to-no effect at EP2, DP, IP and TP prostanoid receptors.

Technical Data for Latanoprost

M. Wt 432.59
Formula C26H40O5
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 130209-82-4
PubChem ID 5311221
Smiles O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](CC[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for Latanoprost

References are publications that support the biological activity of the product.

Stjernschantz (2001) From PGF-isopropyl ester to latanoprost: a review of the development of xalatan: the Proctor Lecture. Invest.Ophthalmol.Vis.Sci. 42 1134 PMID: 11328719

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Keywords: Latanoprost, Latanoprost supplier, Pfizer, latanoprost, prostaglandins, receptors, FP, agonists, EP1, EP3, Prostanoid, Receptors, 4757, Tocris Bioscience

Citations for Latanoprost

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Currently there are no citations for Latanoprost.

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