L-Glutathione Reduced

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Cat.No. 5219 - L-Glutathione Reduced | C10H17N3O6S | CAS No. 70-18-8
Description: Endogenous antioxidant
Alternative Names: GSH
Chemical Name: L-γ-glutamyl-L-cysteinyl-glycine
Purity: ≥98% (HPLC)

Biological Activity

Endogenous antioxidant; reduces reactive oxygen species formed during cellular metabolism. Regulates activity of the redox sensitive transcription factor NF-κB. Cytoprotective.

Technical Data

M. Wt 307.32
Formula C10H17N3O6S
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 70-18-8
PubChem ID 124886
Smiles O=C(N[C@@H](CS)C(NCC(O)=O)=O)CC[C@H](N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 30.73 100

Preparing Stock Solutions

The following data is based on the product molecular weight 307.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.25 mL 16.27 mL 32.54 mL
5 mM 0.65 mL 3.25 mL 6.51 mL
10 mM 0.33 mL 1.63 mL 3.25 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

Molarity Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet


References are publications that support the products' biological activity.

Sen et al (1999) Glutathione homeostasis in response to exercise training and nutritional supplements. Mol.Cell.Biochem. 196 31 PMID: 10448900

Kerksick et al (2005) The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. J.Int.Soc.Sports Nutr. 2 38 PMID: 8500954

If you know of a relevant reference for L-Glutathione Reduced, please let us know.

View Related Products by Target

Keywords: Endogenous antioxidant NF-κB cellular metabolism redox cytoprotective neuroprotective GSH GSH Antioxidants

Citations for L-Glutathione Reduced

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Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for L-Glutathione Reduced


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