L-Glutathione Reduced

Pricing Availability   Qty
Cat.No. 5219 - L-Glutathione Reduced | C10H17N3O6S | CAS No. 70-18-8
Description: Endogenous antioxidant
Alternative Names: GSH
Chemical Name: L-γ-glutamyl-L-cysteinyl-glycine
Purity: ≥98%
Datasheet
Citations (1)
Reviews (1)
Literature

Biological Activity

Endogenous antioxidant; reduces reactive oxygen species formed during cellular metabolism. Regulates activity of the redox sensitive transcription factor NF-κB. Cytoprotective.

Technical Data

M. Wt 307.32
Formula C10H17N3O6S
Storage Store at +4°C
Purity ≥98%
CAS Number 70-18-8
PubChem ID 124886
InChI Key RWSXRVCMGQZWBV-WDSKDSINSA-N
Smiles O=C(N[C@@H](CS)C(NCC(O)=O)=O)CC[C@H](N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 30.73 100

Preparing Stock Solutions

The following data is based on the product molecular weight 307.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.25 mL 16.27 mL 32.54 mL
5 mM 0.65 mL 3.25 mL 6.51 mL
10 mM 0.33 mL 1.63 mL 3.25 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Sen et al (1999) Glutathione homeostasis in response to exercise training and nutritional supplements. Mol.Cell.Biochem. 196 31 PMID: 10448900

Kerksick et al (2005) The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. J.Int.Soc.Sports Nutr. 2 38 PMID: 18500954


If you know of a relevant reference for L-Glutathione Reduced, please let us know.

View Related Products by Target

Keywords: L-Glutathione Reduced, L-Glutathione Reduced supplier, Endogenous, antioxidant, NF-κB, cellular, metabolism, redox, cytoprotective, neuroprotective, GSH, Antioxidants, Amino, Acids, 5219, Tocris Bioscience

1 Citation for L-Glutathione Reduced

Citations are publications that use Tocris products. Selected citations for L-Glutathione Reduced include:

Das et al (2017) Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. Sci Rep 7 40773 PMID: 28112165


Do you know of a great paper that uses L-Glutathione Reduced from Tocris? Please let us know.

Reviews for L-Glutathione Reduced

Average Rating: 5 (Based on 1 Review.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used L-Glutathione Reduced?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


GSH inhibits 15d-PGJ2-induced apoptosis in osteosarcoma cells
By Christopher Trummer on 10/15/2018
Assay Type: In Vitro
Species: Human
Cell Line/Tissue: MG-63 osteosarcoma cells

MG-63 cells were incubated with GSH (10 μM) for 30 min prior to 15d-PGJ2 treatment (20 μM) for 24 h to follow apoptotic markers using Western blot. GSH inhibited 15d-PGJ2-induced PARP and Caspase-3 cleavage.

review image

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


New Product Guide

New Product Guide (Spring/Summer 2018)

Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Aptamers
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells