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L-Glutathione Reduced

Cat. No. 5219 1 Citation Datasheet / COA / SDS
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Cat.No. 5219 - L-Glutathione Reduced | C10H17N3O6S | CAS No. 70-18-8
Description: Endogenous antioxidant
Alternative Names: GSH
Chemical Name: L-γ-glutamyl-L-cysteinyl-glycine
Purity: ≥98%
Datasheet
Citations (1)
Reviews
Literature
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Endogenous antioxidant; reduces reactive oxygen species formed during cellular metabolism. Regulates activity of the redox sensitive transcription factor NF-κB. Cytoprotective.

Technical Data

M. Wt 307.32
Formula C10H17N3O6S
Storage Store at +4°C
Purity ≥98%
CAS Number 70-18-8
PubChem ID 124886
InChI Key RWSXRVCMGQZWBV-WDSKDSINSA-N
Smiles O=C(N[C@@H](CS)C(NCC(O)=O)=O)CC[C@H](N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 30.73 100

Preparing Stock Solutions

The following data is based on the product molecular weight 307.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.25 mL 16.27 mL 32.54 mL
5 mM 0.65 mL 3.25 mL 6.51 mL
10 mM 0.33 mL 1.63 mL 3.25 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Sen et al (1999) Glutathione homeostasis in response to exercise training and nutritional supplements. Mol.Cell.Biochem. 196 31 PMID: 10448900

Kerksick et al (2005) The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. J.Int.Soc.Sports Nutr. 2 38 PMID: 18500954

If you know of a relevant reference for L-Glutathione Reduced, please let us know.

View Related Products by Target

Keywords: L-Glutathione Reduced, supplier, Endogenous, antioxidant, NF-κB, cellular, metabolism, redox, cytoprotective, neuroprotective, GSH, GSH, Antioxidants, Amino, Acids, Antioxidants, Tocris Bioscience

1 Citation for L-Glutathione Reduced

Citations are publications that use Tocris products. Selected citations for L-Glutathione Reduced include:

Das et al (2017) Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. Sci Rep 7 40773 PMID: 28112165

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Literature in this Area

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