L-Canavanine sulfate

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Cat.No. 0673 - L-Canavanine sulfate | C5H12N4O3.H2SO4 | CAS No. 2219-31-0
Description: NOS inhibitor
Chemical Name: L-2-Amino-4-(guanidiooxy)butyric acid sulfate
Datasheet
Citations
Literature

Biological Activity

NO synthase inhibitor.

Technical Data

M. Wt 274.25
Formula C5H12N4O3.H2SO4
Storage Desiccate at +4°C
CAS Number 2219-31-0
PubChem ID 11957500
InChI Key MVIPJKVMOKFIEV-DFWYDOINSA-N
Smiles OS(O)(=O)=O.NC(NOCC[C@H](N)C(O)=O)=N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in water

Preparing Stock Solutions

The following data is based on the product molecular weight 274.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.65 mL 18.23 mL 36.46 mL
5 mM 0.73 mL 3.65 mL 7.29 mL
10 mM 0.36 mL 1.82 mL 3.65 mL
50 mM 0.07 mL 0.36 mL 0.73 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Dokita et al (1994) Involvement of nitric oxide and cyclic GMP in rabbit urethral relaxation. Eur.J.Pharmacol. 269 269 PMID: 7851504

Knowles et al (1994) Nitric oxide synthases in mammals. Biochem.J. 298 249 PMID: 7510950

Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204 PMID: 9226999

Teale and Atkinson (1994) L-Canavanine restores blood pressure in a rat model of endotoxic shock. Eur.J.Pharmacol. 271 87 PMID: 7535234


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Keywords: NOS inhibitors inhibits Non-Selective Nitric Oxide Signaling Signalling NO Synthases iNOS eNOS nNOS Non-selective NOS

Citations for L-Canavanine sulfate

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Literature in this Area

Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
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  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
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Pathways for L-Canavanine sulfate

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