L-(-)-α-Methyldopa

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Cat.No. 0584 - L-(-)-a-Methyldopa | C10H13NO4 | CAS No. 555-30-6
Description: Aromatic L-amino acid decarboxylase inhibitor
Chemical Name: 3-(3,4-Dihydroxyphenyl)-α-methyl-L-alanine
Datasheet
Citations
Literature

Biological Activity

L-aromatic amino acid decarboxylase inhibitor. Antihypertensive.

Technical Data

M. Wt 211.22
Formula C10H13NO4
Storage Store at RT
CAS Number 555-30-6
PubChem ID 38853
InChI Key CJCSPKMFHVPWAR-JTQLQIEISA-N
Smiles OC1=C(O)C=C(C[C@@](N)(C)C(O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 15.84 75

Preparing Stock Solutions

The following data is based on the product molecular weight 211.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.73 mL 23.67 mL 47.34 mL
5 mM 0.95 mL 4.73 mL 9.47 mL
10 mM 0.47 mL 2.37 mL 4.73 mL
50 mM 0.09 mL 0.47 mL 0.95 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Kapoor and Chalmers (1989) Correlation between fall in blood pressure and in vivo amine release after α-methylDOPA. Eur.J.Pharmacol. 164 531 PMID: 2767124

Van Zwieten et al (1984) The hypotensive activity and side effects of methyldopa, clonidine, and guanfacine. Hypertension 6 II-28 PMID: 6094346

Merck Index 12 6132 PMID:


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