Kinetensin (human)

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Cat.No. 1915 - Kinetensin (human) | Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu | CAS No. 103131-69-7
Description: Neurotensin-like peptide
Alternative Names: Neurotensin-related peptide
Datasheet
Citations
Reviews
Literature

Biological Activity

Endogenous neurotensin-like peptide, originally isolated from pepsin-treated human plasma. Induces histamine release from rat peritoneal mast cells in vitro (ED50 ~ 10 mM).

Technical Data

M. Wt 1172.39
Formula C56H85N17O11
Sequence IARRHPYFL
Storage Desiccate at -20°C
CAS Number 103131-69-7
PubChem ID 147043
InChI Key PANUJGMSOSQAAY-IHXGQVBNSA-N
Smiles [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 2 mg/ml in water

References

References are publications that support the biological activity of the product.

Carraway et al (1987) Structure of a biologically active neurotensin-related peptide obtained from pepsin-treated albumin(s). J.Biol.Chem. 262 5968 PMID: 2437111

Mogard et al (1986) The amino acid sequence of kinetensin, a novel peptide isolated from pepsin-treated human plasma: homology with human serum albumin, neurotensin and angiotensin. Biochem.Biophys.Res.Commun. 136 938 PMID: 3087352

Sydbom et al (1989) Stimulation of histamine release by the peptide kinetensin. Agents Actions 27 68 PMID: 2473637


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