Endogenous neurotensin-like peptide, originally isolated from pepsin-treated human plasma. Induces histamine release from rat peritoneal mast cells in vitro (ED50 ~ 10 mM).
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 2 mg/ml in water|
References are publications that support the biological activity of the product.
Carraway et al (1987) Structure of a biologically active neurotensin-related peptide obtained from pepsin-treated albumin(s). J.Biol.Chem. 262 5968 PMID: 2437111
Mogard et al (1986) The amino acid sequence of kinetensin, a novel peptide isolated from pepsin-treated human plasma: homology with human serum albumin, neurotensin and angiotensin. Biochem.Biophys.Res.Commun. 136 938 PMID: 3087352
Sydbom et al (1989) Stimulation of histamine release by the peptide kinetensin. Agents Actions 27 68 PMID: 2473637
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.