You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for IWP L6
IWP L6 is a potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM). Shown to inhibit Wnt-dependent processes such as tailfin regeneration and posterior axis formation in zebrafish; also reduces branching morphogenesis in cultured mouse embryonic kidneys.
Technical Data for IWP L6
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for IWP L6
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for IWP L6
The following data is based on the product molecular weight 472.58. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.12 mL||10.58 mL||21.16 mL|
|5 mM||0.42 mL||2.12 mL||4.23 mL|
|10 mM||0.21 mL||1.06 mL||2.12 mL|
|50 mM||0.04 mL||0.21 mL||0.42 mL|
References for IWP L6
References are publications that support the biological activity of the product.
Wang et al (2013) The development of highly potent inhibitors for Porcupine. J.Med.Chem. 56 2700 PMID: 23477365
If you know of a relevant reference for IWP L6, please let us know.
View Related Products by Product Action
Keywords: IWP L6, IWP L6 supplier, IWPL6, MBOAT, membrane-bound, O-acyltransferases, inhibitors, inhibits, porcupine, porcn, Wnt, PORCN, 4992, Tocris Bioscience
Citations for IWP L6
Citations are publications that use Tocris products.
Currently there are no citations for IWP L6. Do you know of a great paper that uses IWP L6 from Tocris? Please let us know.
Reviews for IWP L6
There are currently no reviews for this product. Be the first to review IWP L6 and earn rewards!
Have you used IWP L6?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.