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IRAK1/4 Inhibitor I
IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 395.41. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||12.65 mL||63.23 mL||126.45 mL|
|1 mM||2.53 mL||12.65 mL||25.29 mL|
|2 mM||1.26 mL||6.32 mL||12.65 mL|
|10 mM||0.25 mL||1.26 mL||2.53 mL|
References are publications that support the biological activity of the product.
Powers et al (2006) Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg.Med.Chem.Lett. 16 2842 PMID: 16563752
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Citations for IRAK1/4 Inhibitor I
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