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IRAK1/4 Inhibitor I
Biological Activity for IRAK1/4 Inhibitor I
IRAK1/4 Inhibitor I is an IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).
Compound Libraries for IRAK1/4 Inhibitor I
Technical Data for IRAK1/4 Inhibitor I
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for IRAK1/4 Inhibitor I
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for IRAK1/4 Inhibitor I
The following data is based on the product molecular weight 395.41. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||12.65 mL||63.23 mL||126.45 mL|
|1 mM||2.53 mL||12.65 mL||25.29 mL|
|2 mM||1.26 mL||6.32 mL||12.65 mL|
|10 mM||0.25 mL||1.26 mL||2.53 mL|
Product Datasheets for IRAK1/4 Inhibitor I
References for IRAK1/4 Inhibitor I
References are publications that support the biological activity of the product.
Powers et al (2006) Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg.Med.Chem.Lett. 16 2842 PMID: 16563752
If you know of a relevant reference for IRAK1/4 Inhibitor I, please let us know.
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Keywords: IRAK1/4 Inhibitor I, IRAK1/4 Inhibitor I supplier, IRAK1/4, inhibitors, inhibits, I, interleukin-1, receptor, associated, kinase, IRAK, 5665, Tocris Bioscience
1 Citation for IRAK1/4 Inhibitor I
Citations are publications that use Tocris products. Selected citations for IRAK1/4 Inhibitor I include:
Shahid et al (2021) SIGIRR Mutation in Human Necrotizing Enterocolitis (NEC) Disrupts STAT3-Dependent microRNA Expression in Neonatal Gut. Cell Mol Gastroenterol Hepatol 13 425-440 PMID: 34563711
Do you know of a great paper that uses IRAK1/4 Inhibitor I from Tocris? Please let us know.
Reviews for IRAK1/4 Inhibitor I
Average Rating: 5 (Based on 1 Review.)
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Literature in this Area
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