Potent σ-receptor antagonist.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 50 mM in ethanol and to 100 mM in DMSO|
Preparing Stock Solutions
The following data is based on the product molecular weight 395.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.53 mL||12.65 mL||25.3 mL|
|5 mM||0.51 mL||2.53 mL||5.06 mL|
|10 mM||0.25 mL||1.26 mL||2.53 mL|
|50 mM||0.05 mL||0.25 mL||0.51 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Whittemore et al (1997) Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326 PMID: 9223571
Wilson et al (1991) Radiosynthesis of σ receptor ligands for positron emission tomography: 11C- and 18F-labelled guanidines. J.Med.Chem. 34 1867 PMID: 1648140
If you know of a relevant reference for IPAG, please let us know.
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Keywords: IPAG, supplier, Potent, σ, sigma, antagonists, General, Receptors, Sigma-Related, Sigma-Related, Tocris Bioscience
1 Citation for IPAG
Citations are publications that use Tocris products. Selected citations for IPAG include:
Kim et al (2012) Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression. Biochem Biophys Res Commun 426 177 PMID: 22925888
Do you know of a great paper that uses IPAG from Tocris? If so please let us know.
Literature in this Area
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