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Biological Activity for iP300v
iP300v is a negative control for iP300w (Cat. No. 7270)
Technical Data for iP300v
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for iP300v
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for iP300v
The following data is based on the product molecular weight 618.55. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.62 mL||8.08 mL||16.17 mL|
|5 mM||0.32 mL||1.62 mL||3.23 mL|
|10 mM||0.16 mL||0.81 mL||1.62 mL|
|50 mM||0.03 mL||0.16 mL||0.32 mL|
References for iP300v
References are publications that support the biological activity of the product.
Bosnakovski et al (2019) A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death. Sci.Adv. 5 eaaw7781 PMID: 31535023
Bosnakovski et al (2021) Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma. Oncogenesis 10 68
If you know of a relevant reference for iP300v, please let us know.
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Keywords: iP300v, iP300v supplier, HAT, Histone, Acetyltransferases, KAT, Lysine, Aceyltransferases, p300, CBP, negative, control, 7584, Tocris Bioscience
Citations for iP300v
Citations are publications that use Tocris products.
Currently there are no citations for iP300v. Do you know of a great paper that uses iP300v from Tocris? Please let us know.
Reviews for iP300v
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Epigenetics Scientific Review
Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.