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A potent histamine H2 receptor antagonist.
Sold with the permission of AstraZeneca UK Ltd.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble in ethanol and to 100 mM in DMSO|
References are publications that support the biological activity of the product.
Gompertz et al (1991) Acid blockade by omeprazole or ICI 162846 in a chronic duodenal ulcer model. Agents Actions 33 161 PMID: 1716826
Streett et al (1988) Morphological stomach findings in rats and mice treated with the H2 receptor antagonists, ICI 125,211 and ICI 162,846. Toxicol.Pathol. 16 299 PMID: 2903545
Wilson et al (1986) Inhibition of human gastric secretion by ICI 162,846 - a new histamine H2 receptor antagonist. Br.J.Clin.Pharmacol. 21 685 PMID: 2874823
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Keywords: ICI 162,846, ICI 162,846 supplier, Potent, H2, antagonists, active, vivo, Receptors, Histamine, histaminergic, ICI162846, AstraZeneca, 0833, Tocris Bioscience
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