Discontinued Product

Hypericin (Cat. No. 1520) has been withdrawn from sale for commercial reasons.
Cat.No. 1520 - Hypericin | C30H16O8 | CAS No. 548-04-9
Description: Inhibits tyrosine kinases
Chemical Name: 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
Purity: ≥98% (HPLC)
Citations (1)
Literature (2)

Biological Activity for Hypericin

Photosensitive antiviral, anticancer and antidepressant agent derived from Hypericum perforatum (St John's wort). Inactivates enveloped viruses (including HIV), inhibits tyrosine kinases (IC50 = 7.5 μM) and is preferentially cytotoxic to tumor cells upon stimulation by visible light.

Technical Data for Hypericin

M. Wt 504.45
Formula C30H16O8
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 548-04-9
PubChem ID 5281051
Smiles OC1=C(C5=C(O)C=C(O)C4=C56)C(C(C(C(C7=C(C)C=C8O)=C(C)C=C3O)=C3C2=O)=C6C7=C8C4=O)=C2C(O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Hypericin

Certificate of Analysis / Product Datasheet
Select another batch:

References for Hypericin

References are publications that support the biological activity of the product.

Agostinis et al (2002) Hypericin in cancer treatment: more light on the way. Int.J.Biochem.Cell Biol. 34 221 PMID: 11849990

Hwang et al (2001) Inhibition of c-erbB-2 expression and activity in human ovarian carcinoma cells by hypericin. Anticancer Res. 21 2649 PMID: 11724334

Lenard et al (1993) Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses using hypericin and rose bengal: inhibition of fusion and syncytia formation. Proc.Natl.Acad.Sci.U.S.A. 90 158 PMID: 7678335

View Related Products by Product Action

View all Broad Spectrum Protein Kinase Inhibitor Inhibitors

Keywords: Hypericin, Hypericin supplier, inhibitors, inhibits, tyrosine, kinases, Protein, Kinase, Broad, Spectrum, Inhibitors, Non-selective, Antivirals, 1520, Tocris Bioscience

1 Citation for Hypericin

Citations are publications that use Tocris products. Selected citations for Hypericin include:

Chen et al (2018) Concomitant SK current activation and sodium current inhibition cause J wave syndrome. JCI Insight 3 PMID: 30429367

Reviews for Hypericin

There are currently no reviews for this product. Be the first to review Hypericin and earn rewards!

Have you used Hypericin?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cancer Research Product Guide

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Kinases Product Listing

Kinases Product Listing

A collection of over 400 products for kinase research, the listing includes inhibitors of:

  • Receptor Tyrosine Kinases
  • Protein Kinases A, C, D and G
  • PI-3 Kinase, Akt and mTOR
  • MAPK Signaling
  • Receptor Serine/Threonine Kinases