You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
ATP-competitive inhibitor of DAPK (IC50 = 200 nM) and ZIPK (Kd = 280 nM). Also inhibits PIM3 kinase (IC50 = 200 nM) but exhibits no significant effect on Src or Abl kinases. Reduces phosphorylation of regulatory myosin light chain and myosin light chain phosphatase in mouse aortic and rabbit ileal tissues.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 349.8. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||5.72 mL||28.59 mL||57.18 mL|
|2.5 mM||1.14 mL||5.72 mL||11.44 mL|
|5 mM||0.57 mL||2.86 mL||5.72 mL|
|25 mM||0.11 mL||0.57 mL||1.14 mL|
References are publications that support the biological activity of the product.
MacDonald et al (2016) A Small Molecule Pyrazolo[3,4-d]Pyrimidinone Inhibitor of Zipper-Interacting Protein Kinase Suppresses Calcium Sensitization of Vascular Smooth Muscle. Mol.Pharmacol. 89 105 PMID: 26464323
Carlson et al (2013) Fluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor. ACS.Chem.Biol. 8 2715 PMID: 24070067
If you know of a relevant reference for HS 38, please let us know.
View Related Products by Product Action
Keywords: HS 38, HS 38 supplier, HS38, ATP-competitive, inhibitors, inhibits, DAPK, ZIPK, PIM3, kinase, regulatory, myosin, light, chain, llight, phosphatase, 5768, Tocris Bioscience
Citations for HS 38
Citations are publications that use Tocris products.
Currently there are no citations for HS 38. Do you know of a great paper that uses HS 38 from Tocris? Please let us know.
Reviews for HS 38
There are currently no reviews for this product. Be the first to review HS 38 and earn rewards!
Have you used HS 38?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.