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HM 50316 is a high affinity FABP4 inhibitor (Ki < 1 nM). Highly selective for FABP4 over FABP3. Inhibits LPS-induced activation of murine macrophages in vitro.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Liu et al (2011) New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein. Bioorg.Med.Chem.Lett. 21 2949 PMID: 21481589
Keywords: HM 50316, HM 50316 supplier, HM50316, fatty, acid-binding, protein, adipocyte, a-FABP, FABP4, inhibitors, inhibits, high, affinity, Fatty, Acid, Binding, Proteins, 5850, Tocris Bioscience
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