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Insulin-regulated aminopeptidase (IRAP) inhibitor (Ki = 2.01 μM). Improves memory in control and memory-deficient mice models.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Albiston et al (2010) Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of Ins-regulated aminopeptidase. Mol.Pharmacol. 78 600 PMID: 20628006
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Keywords: HFI 142, HFI 142 supplier, HFI, 142, inhibitors, inhibits, insulin-regulated, aminopeptidases, IRAPs, memory, Aminopeptidases, 5627, Tocris Bioscience
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