Insulin-regulated aminopeptidase (IRAP) inhibitor (Ki = 2.01 μM). Improves memory in control and memory-deficient mice models.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|ethanol||3.12||10mM with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 312.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.2 mL||16.01 mL||32.02 mL|
|5 mM||0.64 mL||3.2 mL||6.4 mL|
|10 mM||0.32 mL||1.6 mL||3.2 mL|
|50 mM||0.06 mL||0.32 mL||0.64 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Albiston et al (2010) Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase. Mol.Pharmacol. 78 600 PMID: 20628006
If you know of a relevant reference for HFI 142, please let us know.
View Related Products by Product Action
Keywords: HFI 142, supplier, HFI, 142, inhibitors, inhibits, insulin-regulated, aminopeptidases, IRAPs, memory, Aminopeptidases, Aminopeptidases, Tocris Bioscience
Citations for HFI 142
Citations are publications that use Tocris products.
Currently there are no citations for HFI 142. Do you know of a great paper that uses HFI 142 from Tocris? If so please let us know.
Literature in this Area
New Product Guide (Spring/Summer 2017)New
Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Cell Metabolism
- Fluorescent Imaging
- Signal Transduction
- Stem Cells