Hexa-D-arginine

Pricing Availability Delivery Time Qty
Cat.No. 4711 - Hexa-D-arginine | D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2 | CAS No. 673202-67-0
Description: Furin inhibitor
Datasheet
Citations
Literature

Biological Activity

Inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).

Technical Data

M. Wt 954.16
Formula C36H75N25O6
Sequence RRRRRR

(Modifications: Arg-6 = C-terminal amide, Arg-1,2,3,4,5,6=D-Arg)

Storage Store at -20°C
CAS Number 673202-67-0
PubChem ID 57358476
InChI Key BMLTZEAFQLJTIZ-TZNXUKFXSA-N
Smiles [H]N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 2 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 954.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.05 mL 5.24 mL 10.48 mL
5 mM 0.21 mL 1.05 mL 2.1 mL
10 mM 0.1 mL 0.52 mL 1.05 mL
50 mM 0.02 mL 0.1 mL 0.21 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

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View all Other Protease Inhibitors

Keywords: Hexa-D-arginine selective furin inhibitors inhibits paired basic amino acid cleaving enzyme PACE subtilisin-like proprotein convertases Other Proteases

Citations for Hexa-D-arginine

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New Product Guide (Spring/Summer 2017)

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Pathways for Hexa-D-arginine

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