You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for GSK 9027
GSK 9027 is a glucocorticoid receptor agonist (pIC50 = 8). Inhibits production of the proinflammatory mediator IL-6 in vivo.
Sold for research purposes under agreement from GlaxoSmithKline.
Technical Data for GSK 9027
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for GSK 9027
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for GSK 9027
The following data is based on the product molecular weight 525.52. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.9 mL||9.51 mL||19.03 mL|
|5 mM||0.38 mL||1.9 mL||3.81 mL|
|10 mM||0.19 mL||0.95 mL||1.9 mL|
|50 mM||0.04 mL||0.19 mL||0.38 mL|
References for GSK 9027
References are publications that support the biological activity of the product.
Yates et al (2010) Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists. J.Med.Chem. 53 4531 PMID: 20469868
If you know of a relevant reference for GSK 9027, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: GSK 9027, GSK 9027 supplier, gsk, GSK9027, glucocorticoid, receptors, agonists, Glucocorticoid, Receptor, 4116, Tocris Bioscience
Citations for GSK 9027
Citations are publications that use Tocris products.
Currently there are no citations for GSK 9027. Do you know of a great paper that uses GSK 9027 from Tocris? Please let us know.
Reviews for GSK 9027
There are currently no reviews for this product. Be the first to review GSK 9027 and earn rewards!
Have you used GSK 9027?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.