Glucocorticoid receptor agonist (pIC50 = 8). Inhibits production of the proinflammatory mediator IL-6 in vivo.
Sold for research purposes under agreement from GlaxoSmithKline.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 525.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.9 mL||9.51 mL||19.03 mL|
|5 mM||0.38 mL||1.9 mL||3.81 mL|
|10 mM||0.19 mL||0.95 mL||1.9 mL|
|50 mM||0.04 mL||0.19 mL||0.38 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Yates et al (2010) Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists. J.Med.Chem. 53 4531 PMID: 20469868
If you know of a relevant reference for GSK 9027, please let us know.
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Keywords: GSK 9027, supplier, gsk, GSK9027, glucocorticoid, receptors, agonists, Glucocorticoid, Receptor, Tocris Bioscience
Citations for GSK 9027
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