You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for GSK 4716
GSK 4716 is a selective agonist at estrogen-related receptors ERRβ and ERRγ. Displays selectivity over ERRα and the classical estrogen receptors.
Technical Data for GSK 4716
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for GSK 4716
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for GSK 4716
The following data is based on the product molecular weight 282.34. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.54 mL||17.71 mL||35.42 mL|
|5 mM||0.71 mL||3.54 mL||7.08 mL|
|10 mM||0.35 mL||1.77 mL||3.54 mL|
|50 mM||0.07 mL||0.35 mL||0.71 mL|
References for GSK 4716
References are publications that support the biological activity of the product.
Zuercher et al (2005) Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRβ and ERRγ. J.Med.Chem. 48 3107 PMID: 15857113
Ariazi and Jordan (2006) Estrogen-related receptors as emerging targets in cancer and metabolic disorders. Curr.Top.Med.Chem. 6 203 PMID: 16515477
Wang et al (2006) X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation. J.Biol.Chem. 281 37773 PMID: 16990259
If you know of a relevant reference for GSK 4716, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: GSK 4716, GSK 4716 supplier, Selective, ERRγ, ERRgamma, ERRβ, ERRbeta, agonists, Estrogen, related, Receptors, GSK4716, GW4716, and, Related, 3075, Tocris Bioscience
1 Citation for GSK 4716
Citations are publications that use Tocris products. Selected citations for GSK 4716 include:
Weber et al (2014) Bisphenol A exposure during early development induces sex-specific changes in adult zebrafish social interactions. J Toxicol Environ Health A 78 50 PMID: 25424546
Do you know of a great paper that uses GSK 4716 from Tocris? Please let us know.
Reviews for GSK 4716
There are currently no reviews for this product. Be the first to review GSK 4716 and earn rewards!
Have you used GSK 4716?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.