GR 79236

Discontinued Product

GR 79236 (Cat. No. 1957) has been withdrawn from sale for commercial reasons.
Description: A1 agonist
Chemical Name: N-[(1S,2S)-2-Hydroxycyclopentyl]adenosine
Purity: ≥99% (HPLC)

Biological Activity for GR 79236

Adenosine A1 receptor agonist (Ki = 3.1 nM). Anticonvulsive in mice following systemic administration in vivo.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline

Technical Data for GR 79236

M. Wt 351.36
Formula C15H21N5O5
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 124555-18-6
PubChem ID 9884817
Smiles O[C@@H](CCC4)[C@H]4NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for GR 79236

Certificate of Analysis / Product Datasheet
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References for GR 79236

References are publications that support the biological activity of the product.

Gurden et al (1993) Functional characterization of three adenosine receptor types. Br.J.Pharmacol. 109 693 PMID: 8358566

Knutsen et al (1999) N-Substituted adenosines as novel neuroprotective A1 agonists with diminished hypotensive effects. J.Med.Chem. 42 3463 PMID: 10479279

Merkel et al (1995) Cardiovascular and antilipolytic effects of the adenosine agonist GR 79236. Pharmacology 51 224 PMID: 8577816

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Keywords: GR 79236, GR 79236 supplier, A1, agonists, Receptors, adenosines, GR79236, GlaxoSmithKline, GSK, Adenosine, 1957, Tocris Bioscience

Citations for GR 79236

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Currently there are no citations for GR 79236.

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