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Submit ReviewGR 79236
Discontinued Product
GR 79236 (Cat. No. 1957) has been withdrawn from sale for commercial reasons.
Description: A1 agonist
Chemical Name: N-[(1S,2S)-2-Hydroxycyclopentyl]adenosine
Purity: ≥99% (HPLC)
Biological Activity for GR 79236
Adenosine A1 receptor agonist (Ki = 3.1 nM). Anticonvulsive in mice following systemic administration in vivo.
Licensing Information
Sold for research purposes under agreement from GlaxoSmithKline
Technical Data for GR 79236
| M. Wt | 351.36 |
| Formula | C15H21N5O5 |
| Storage | Desiccate at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 124555-18-6 |
| PubChem ID | 9884817 |
| InChI Key | GYWXTRVEUURNEW-TVDBPQCTSA-N |
| Smiles | O[C@@H](CCC4)[C@H]4NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for GR 79236
References for GR 79236
References are publications that support the biological activity of the product.
Gurden et al (1993) Functional characterization of three adenosine receptor types. Br.J.Pharmacol. 109 693 PMID: 8358566
Knutsen et al (1999) N-Substituted adenosines as novel neuroprotective A1 agonists with diminished hypotensive effects. J.Med.Chem. 42 3463 PMID: 10479279
Merkel et al (1995) Cardiovascular and antilipolytic effects of the adenosine agonist GR 79236. Pharmacology 51 224 PMID: 8577816
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Keywords: GR 79236, GR 79236 supplier, A1, agonists, Receptors, adenosines, GR79236, GlaxoSmithKline, GSK, Adenosine, 1957, Tocris Bioscience
Citations for GR 79236
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Currently there are no citations for GR 79236.
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