Discontinued Product

Gly-Pro-Arg-Pro (Cat. No. 1805) has been withdrawn from sale for commercial reasons.
Description: Inhibits fibrin polymerization
Alternative Names: Anti-polymerant peptide,GPRP

Biological Activity for Gly-Pro-Arg-Pro

Inhibitor of fibrin polymerization; binds to fibrinogen (Ki = 400 mM). Anticoagulant.

Technical Data for Gly-Pro-Arg-Pro

M. Wt 425.49
Formula C18H31N7O5
Sequence GPRP
Storage Desiccate at -20°C
CAS Number 67869-62-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Gly-Pro-Arg-Pro

References for Gly-Pro-Arg-Pro

References are publications that support the biological activity of the product.

Hsieh et al (1981) Fibrin polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J.Med.Chem. 24 322 PMID: 7265118

Laudano and Doolittle (1980) Studies on synthetic peptides that bind to fibrinogen and prevent fibrin polymerization. Structural requirements, number of binding sites, and species differences. Biochemistry 19 1013 PMID: 7356959

Laudano and Doolittle (1978) Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers Proc.Natl.Acad.Sci.U.S.A. 75 3085 PMID: 277910

Keywords: Gly-Pro-Arg-Pro, Gly-Pro-Arg-Pro supplier, inhibitors, inhibits, fibrin, polymerization, Glycoprotein, IIb/IIIa, αIIbα3, alphaIIbalpha3, E, Selectin, ICAM, NCAM, P-Selectin, Laminin, Annexin, Lipocortin, 1, Selectins, Adhesion, Molecules, Anti-polymerant, peptide, GPRP, Cell, 1805, Tocris Bioscience

Citations for Gly-Pro-Arg-Pro

Citations are publications that use Tocris products.

Currently there are no citations for Gly-Pro-Arg-Pro.

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