Discontinued ProductUnfortunately Gly-Pro-Arg-Pro (Cat. No. 1805) has been withdrawn from sale for commercial reasons.
Inhibitor of fibrin polymerization; binds to fibrinogen (Ki = 400 mM). Anticoagulant.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 425.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.35 mL||11.75 mL||23.5 mL|
|5 mM||0.47 mL||2.35 mL||4.7 mL|
|10 mM||0.24 mL||1.18 mL||2.35 mL|
|50 mM||0.05 mL||0.24 mL||0.47 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Hsieh et al (1981) Fibrin polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J.Med.Chem. 24 322 PMID: 7265118
Laudano and Doolittle (1980) Studies on synthetic peptides that bind to fibrinogen and prevent fibrin polymerization. Structural requirements, number of binding sites, and species differences. Biochemistry 19 1013 PMID: 7356959
Laudano and Doolittle (1978) Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers Proc.Natl.Acad.Sci.U.S.A. 75 3085 PMID: 277910
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Keywords: inhibitors inhibits fibrin polymerization Glycoprotein IIb/IIIa αIIbα3 alphaIIbalpha3 E Selectin ICAM NCAM P-Selectin Laminin Annexin Lipocortin 1 Selectins Adhesion Molecules Anti-polymerant peptide GPRP Cell Adhesion Molecules
Citations for Gly-Pro-Arg-Pro
Citations are publications that use Tocris products.
Currently there are no citations for Gly-Pro-Arg-Pro.