Gly-Pro-Arg-Pro

Discontinued Product

Unfortunately Gly-Pro-Arg-Pro (Cat. No. 1805) has been withdrawn from sale for commercial reasons.
Cat.No. 1805 - Gly-Pro-Arg-Pro | Gly-Pro-Arg-Pro | CAS No. 67869-62-9
Description: Inhibits fibrin polymerization
Alternative Names: Anti-polymerant peptide, GPRP
Datasheet
Citations
Reviews
Literature

Biological Activity

Inhibitor of fibrin polymerization; binds to fibrinogen (Ki = 400 mM). Anticoagulant.

Technical Data

M. Wt 425.49
Formula C18H31N7O5
Sequence GPRP
Storage Desiccate at -20°C
CAS Number 67869-62-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Hsieh et al (1981) Fibrin polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J.Med.Chem. 24 322 PMID: 7265118

Laudano and Doolittle (1980) Studies on synthetic peptides that bind to fibrinogen and prevent fibrin polymerization. Structural requirements, number of binding sites, and species differences. Biochemistry 19 1013 PMID: 7356959

Laudano and Doolittle (1978) Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers Proc.Natl.Acad.Sci.U.S.A. 75 3085 PMID: 277910

Keywords: Gly-Pro-Arg-Pro, supplier, inhibitors, inhibits, fibrin, polymerization, Glycoprotein, IIb/IIIa, αIIbα3, alphaIIbalpha3, E, Selectin, ICAM, NCAM, P-Selectin, Laminin, Annexin, Lipocortin, 1, Selectins, Adhesion, Molecules, Anti-polymerant, peptide, GPRP, Cell, Adhesion, Molecules, Cell, Adhesion, Molecules, Tocris Bioscience

Citations for Gly-Pro-Arg-Pro

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Currently there are no citations for Gly-Pro-Arg-Pro.

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Literature in this Area

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