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Submit ReviewGly-Pro-Arg-Pro
Description: Inhibits fibrin polymerization
Alternative Names: Anti-polymerant peptide,GPRP
Biological Activity for Gly-Pro-Arg-Pro
Inhibitor of fibrin polymerization; binds to fibrinogen (Ki = 400 mM). Anticoagulant.
Technical Data for Gly-Pro-Arg-Pro
| M. Wt | 425.49 |
| Formula | C18H31N7O5 |
| Sequence | GPRP |
| Storage | Desiccate at -20°C |
| CAS Number | 67869-62-9 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Gly-Pro-Arg-Pro
References for Gly-Pro-Arg-Pro
References are publications that support the biological activity of the product.
Hsieh et al (1981) Fibrin polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J.Med.Chem. 24 322 PMID: 7265118
Laudano and Doolittle (1980) Studies on synthetic peptides that bind to fibrinogen and prevent fibrin polymerization. Structural requirements, number of binding sites, and species differences. Biochemistry 19 1013 PMID: 7356959
Laudano and Doolittle (1978) Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers Proc.Natl.Acad.Sci.U.S.A. 75 3085 PMID: 277910
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Citations for Gly-Pro-Arg-Pro
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