Endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Stimulates gastric acid secretion.
(Modifications: X = Glp, Phe-17 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in 1% Ammonia with sonication|
Preparing Stock Solutions
The following data is based on the product molecular weight 2098.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.48 mL||2.38 mL||4.77 mL|
|5 mM||0.1 mL||0.48 mL||0.95 mL|
|10 mM||0.05 mL||0.24 mL||0.48 mL|
|50 mM||0.01 mL||0.05 mL||0.1 mL|
References are publications that support the biological activity of the product.
Noble et al (1999) International union of pharmacology XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol.Rev. 51 745 PMID: 10581329
Blandizzi et al (1999) CCK1 and CCK2 receptors regulate gastric pepsinogen secretion. Eur.J.Pharmacol. 373 71 PMID: 10408253
If you know of a relevant reference for Gastrin I (human), please let us know.
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Keywords: Gastrin I (human), Gastrin I (human) supplier, Selective, CCK2, agonists, Cholecystokinin2, Receptors, GastrinI, (human), organoids, Receptor, 3006, Tocris Bioscience
1 Citation for Gastrin I (human)
Citations are publications that use Tocris products. Selected citations for Gastrin I (human) include:
Bartfeld et al (2015) In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection. Front Cell Neurosci 148 126 PMID: 25307862
Do you know of a great paper that uses Gastrin I (human) from Tocris? Please let us know.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.