Gastrin I (human)

Pricing Availability   Qty
Cat.No. 3006 - Gastrin I (human) | Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2 | CAS No. 10047-33-3
Description: Selective CCK2 agonist
Datasheet
Citations (1)
Reviews
Literature

Biological Activity

Endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Stimulates gastric acid secretion.

Technical Data

M. Wt 2098.22
Formula C97H124N20O31S
Sequence XGPWLEEEEEAYGWMDF

(Modifications: X = Glp, Phe-17 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 10047-33-3
PubChem ID 16162108
InChI Key GKDWRERMBNGKCZ-RNXBIMIWSA-N
Smiles [H]N1[C@@H](CCC1=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in 1% Ammonia with sonication

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Noble et al (1999) International union of pharmacology XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol.Rev. 51 745 PMID: 10581329

Blandizzi et al (1999) CCK1 and CCK2 receptors regulate gastric pepsinogen secretion. Eur.J.Pharmacol. 373 71 PMID: 10408253


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Keywords: Gastrin I (human), Gastrin I (human) supplier, Selective, CCK2, agonists, Cholecystokinin2, Receptors, GastrinI, (human), organoids, Receptor, 3006, Tocris Bioscience

1 Citation for Gastrin I (human)

Citations are publications that use Tocris products. Selected citations for Gastrin I (human) include:

Bartfeld et al (2015) In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection. Front Cell Neurosci 148 126 PMID: 25307862


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Literature in this Area

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