Galanin (porcine)

Pricing Availability Delivery Time Qty
Cat.No. 3008 - Galanin (porcine) | Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-His-Asp-Lys-Tyr-Gly-Leu-Ala-NH2 | CAS No. 88813-36-9
Description: Galanin receptor agonist
Datasheet
Citations
Literature

Biological Activity

Endogenous porcine galanin receptor agonist (pKi values are 9.63, 9.49, 9.02, 8.98, 8.01 and 8.14 at hGAL1, rGAL1, hGAL2, rGAL2, hGAL3 and rGAL3 respectively). Significantly increases food intake under free access conditions and also has roles in learning and memory, anxiety and sexual behavior.

Technical Data

M. Wt 3210.55
Formula C146H213N43O40
Sequence GWTLNSAGYLLGPHAIDNHRSFHDKYGLA

(Modifications: Ala-29 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 88813-36-9
PubChem ID 16133811
InChI Key SLZIZIJTGAYEKK-CIJSCKBQSA-N
Smiles [H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 0.50 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3210.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.31 mL 1.56 mL 3.11 mL
5 mM 0.06 mL 0.31 mL 0.62 mL
10 mM 0.03 mL 0.16 mL 0.31 mL
50 mM 0.01 mL 0.03 mL 0.06 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Brewer and Robinson (2008) Galanin stimulation of feeding is blocked by the addition of a response element. Behav.Neurosci. 122 949 PMID: 18729649

Branchek et al (2000) Galanin receptor subtypes. TiPS. 21 109 PMID:

Tachibana et al (2008) Central administration of galanin stimulates feeding behavior in chicks. Comp.Biochem.Physiol.A.Mol.Inter.Physiol. 151 637 PMID:


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Citations for Galanin (porcine)

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Peptides Involved in Appetite Modulation Scientific Review

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Pathways for Galanin (porcine)

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