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Submit ReviewGalanin (porcine)
Description: Galanin receptor agonist
Biological Activity for Galanin (porcine)
Galanin (porcine) is an endogenous porcine galanin receptor agonist (pKi values are 9.63, 9.49, 9.02, 8.98, 8.01 and 8.14 at hGAL1, rGAL1, hGAL2, rGAL2, hGAL3 and rGAL3 respectively). Significantly increases food intake under free access conditions and also has roles in learning and memory, anxiety and sexual behavior.
Technical Data for Galanin (porcine)
| M. Wt | 3210.55 |
| Formula | C146H213N43O40 |
| Sequence |
GWTLNSAGYLLGPHAIDNHRSFHDKYGLA (Modifications: Ala-29 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 88813-36-9 |
| PubChem ID | 16133811 |
| InChI Key | SLZIZIJTGAYEKK-CIJSCKBQSA-N |
| Smiles | [H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Galanin (porcine)
References for Galanin (porcine)
References are publications that support the biological activity of the product.
Brewer and Robinson (2008) Galanin stimulation of feeding is blocked by the addition of a response element. Behav.Neurosci. 122 949 PMID: 18729649
Branchek et al (2000) Galanin receptor subtypes. TiPS. 21 109
Tachibana et al (2008) Central administration of galanin stimulates feeding behavior in chicks. Comp.Biochem.Physiol.A.Mol.Inter.Physiol. 151 637
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Keywords: Galanin (porcine), Galanin (porcine) supplier, Galanin, receptor, agonists, GAL, Receptors, 3008, Tocris Bioscience
Citations for Galanin (porcine)
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Currently there are no citations for Galanin (porcine).
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.