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Galanin (porcine)

Cat. No. 3008 Submit a Review Datasheet / COA / SDS
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Cat.No. 3008 - Galanin (porcine) | Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-His-Asp-Lys-Tyr-Gly-Leu-Ala-NH2 | CAS No. 88813-36-9
Description: Galanin receptor agonist
Datasheet
Citations
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Literature
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Endogenous porcine galanin receptor agonist (pKi values are 9.63, 9.49, 9.02, 8.98, 8.01 and 8.14 at hGAL1, rGAL1, hGAL2, rGAL2, hGAL3 and rGAL3 respectively). Significantly increases food intake under free access conditions and also has roles in learning and memory, anxiety and sexual behavior.

Technical Data

M. Wt 3210.55
Formula C146H213N43O40
Sequence GWTLNSAGYLLGPHAIDNHRSFHDKYGLA

(Modifications: Ala-29 = C-terminal amide)
Storage Desiccate at -20°C
CAS Number 88813-36-9
PubChem ID 16133811
InChI Key SLZIZIJTGAYEKK-CIJSCKBQSA-N
Smiles [H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 0.50 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3210.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.31 mL 1.56 mL 3.11 mL
5 mM 0.06 mL 0.31 mL 0.62 mL
10 mM 0.03 mL 0.16 mL 0.31 mL
50 mM 0.01 mL 0.03 mL 0.06 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the biological activity of the product.

Brewer and Robinson (2008) Galanin stimulation of feeding is blocked by the addition of a response element. Behav.Neurosci. 122 949 PMID: 18729649

Branchek et al (2000) Galanin receptor subtypes. TiPS. 21 109

Tachibana et al (2008) Central administration of galanin stimulates feeding behavior in chicks. Comp.Biochem.Physiol.A.Mol.Inter.Physiol. 151 637

If you know of a relevant reference for Galanin (porcine), please let us know.

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Keywords: Galanin (porcine), Galanin (porcine) supplier, Galanin, receptor, agonists, GAL, Receptors, 3008, Tocris Bioscience

Citations for Galanin (porcine)

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Literature in this Area

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