Galanin (2-29) (rat)

Pricing Availability Delivery Time Qty
Cat.No. 1451 - Galanin (2-29) (rat) | Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-His-Gly-Leu-Thr-NH2 | CAS No. 141696-11-9
Description: Selective GAL2 peptide agonist
Datasheet
Citations

Biological Activity

Peptide agonist for galanin receptors, showing selectivity for GAL2 (Ki values are 85, 1.9 and 12.6 nM at rat GAL1, GAL2 and GAL3 receptors respectively).

Technical Data

M. Wt 3107.42
Formula C139H207N42O40
Sequence WTLNSAGYLLGPHAIDNHRSFSDKHGLT

(Modifications: Thr-28 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 141696-11-9
PubChem ID 90469976
InChI Key ACSWKWWDLCUVJF-QTRPWDSUSA-N
Smiles [H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC=N1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 0.60 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3107.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.32 mL 1.61 mL 3.22 mL
5 mM 0.06 mL 0.32 mL 0.64 mL
10 mM 0.03 mL 0.16 mL 0.32 mL
50 mM 0.01 mL 0.03 mL 0.06 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Amiranoff et al (1989) Structural requirements for galanin action in the pancreatic β cell line rin m 5F. Eur.J.Pharmacol. 163 205 PMID: 2472967

Wang et al (1997) Cloning and expressional characterization of a novel galanin receptor. J.Biol.Chem. 272 31949 PMID: 9405385

Wang et al (1997) Molecular cloning and pharmacological characterization of a new galanin receptor subtype. Mol.Pharmacol. 52 337 PMID: 9281594


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Keywords: Selective GAL2 GalR2 peptide agonists Receptors Galanin Galanin Receptors

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