Galanin (1-30) (human)

Pricing Availability Delivery Time Qty
Cat.No. 1179 - Galanin (1-30) (human) | Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser | CAS No. 119418-04-1
Description: Endogenous galanin receptor agonist
Datasheet
Citations (1)
Literature

Biological Activity

Endogenous peptide with multiple endocrine, metabolic and behavioral effects. Has been shown to have an action on intestinal smooth muscle, insulin and somatostatin release, and synaptic neurotransmission.

Technical Data

M. Wt 3157.41
Formula C139H210N42O43
Sequence GWTLNSAGYLLGPHAVGNHRSFSDKNGLTS
Storage Desiccate at -20°C
CAS Number 119418-04-1
PubChem ID 16133823
InChI Key CBSXZYWGVAQSHI-RUKUCZSXSA-N
Smiles [H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 0.50 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3157.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.32 mL 1.58 mL 3.17 mL
5 mM 0.06 mL 0.32 mL 0.63 mL
10 mM 0.03 mL 0.16 mL 0.32 mL
50 mM 0.01 mL 0.03 mL 0.06 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Niiro et al (1998) Mechanisms of galanin-induced contraction in the rat myometrium. Br.J.Pharmacol. 124 1623 PMID: 9756377

Schmidt et al (1991) Isolation and primary structure of pituitary human galanin, a 30-residue nonamidated neuropeptide. Proc.Natl.Acad.Sci.U.S.A. 88 11435 PMID: 1722333

Wang et al (1998) Hypothalamic galanin: control by signals of fat metabolism. Brain Res. 804 7 PMID: 9729239


If you know of a relevant reference for Galanin (1-30) (human), please let us know.

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Keywords: Endogenous galanin agonists GAL GalR Receptors Galanin Galanin Receptors

1 Citation for Galanin (1-30) (human)

Citations are publications that use Tocris products. Selected citations for Galanin (1-30) (human) include:

Chiu et al (2013) Bacteria activate sensory neurons that modulate pain and inflammation. Nature 501 52 PMID: 23965627


Do you know of a great paper that uses Galanin (1-30) (human) from Tocris? If so please let us know.

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