Galanin (1-29) (rat, mouse)

Pricing Availability Delivery Time Qty
Cat.No. 2696 - Galanin (1-29) (rat, mouse) | Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-His-Gly-Leu-Thr-NH2 | CAS No. 114547-31-8
Description: Non-selective galanin receptor agonist
Datasheet
Citations (1)
Literature

Biological Activity

Non-selective galanin receptor agonist (Ki values are 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.

Technical Data

M. Wt 3164.48
Formula C141H211N43O41
Sequence GWTLNSAGYLLGPHAIDNHRSFSDKHGLT

(Modifications: Thr-29 = C-terminal amide)

Storage Store at -20°C
CAS Number 114547-31-8
PubChem ID 16201477
InChI Key JHQDYHHNJBOXKP-UPNHMZDKSA-N
Smiles [H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC=N1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3164.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.32 mL 1.58 mL 3.16 mL
5 mM 0.06 mL 0.32 mL 0.63 mL
10 mM 0.03 mL 0.16 mL 0.32 mL
50 mM 0.01 mL 0.03 mL 0.06 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Wang et al (1997) Cloning and expression characterization of a novel galanin receptor. J.Biol.Chem. 272 51 PMID: 8995226

Mazarati et al (2006) Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: the effects of subtype-selective agonists and the role of G-protein-mediated signaling. J.Pharmacol.Exp.Ther. 318 700 PMID: 16699066

Branchek et al (2000) Galanin receptor subtypes. TiPS. 21 109 PMID:


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Keywords: Galanin (1-29) (rat, mouse), supplier, Non-Selective, galanin, receptors, agonists, GAL, GalR, Galanin, Receptors, Tocris Bioscience

1 Citation for Galanin (1-29) (rat, mouse)

Citations are publications that use Tocris products. Selected citations for Galanin (1-29) (rat, mouse) include:

Zhang (2017) Involvement of galanin and galanin receptor 2 in nociceptive modulation in anterior cingulatecortex of normal rats and rats with mononeuropathy. Sci Rep 7 45930 PMID: 28378856


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