Galanin (1-15) (porcine, rat)

Pricing Availability Delivery Time Qty
Cat.No. 1450 - Galanin (1-15) (porcine, rat) | Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala | CAS No. 112747-70-3
Description: Galanin receptor agonist peptide
Datasheet
Citations (1)
Literature

Biological Activity

N-terminal galanin fragment. In contrast to the full length (1-29) peptide, mediates central cardiovascular effects, perhaps by binding to a novel receptor type.

Technical Data

M. Wt 1556.74
Formula C72H105N19O20
Sequence GWTLNSAGYLLGPHA
Storage Desiccate at -20°C
CAS Number 112747-70-3
PubChem ID 16131409
InChI Key LOXLDVDBPRBBLT-GDRYISODSA-N
Smiles [H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1556.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.64 mL 3.21 mL 6.42 mL
5 mM 0.13 mL 0.64 mL 1.28 mL
10 mM 0.06 mL 0.32 mL 0.64 mL
50 mM 0.01 mL 0.06 mL 0.13 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Amiranoff et al (1989) Structural requirements for galanin action in the pancreatic β cell line rin m 5F. Eur.J.Pharmacol. 163 205 PMID: 2472967

Narvaez et al (2000) The galanin receptor antagonist M40 blocks the central cardiovascular actions of the galanin N-terminal fragment (1-15). Eur.J.Pharmacol. 399 197 PMID: 10884520

Xu et al (1999) Electrophysiological evidence for a hyperpolarizing, galanin (1-15)-selective receptor on hippocampal CA3 pyramidal neurons. Proc.Natl.Acad.Sci.USA 96 14583 PMID: 10588748


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Keywords: Galanin (1-15) (porcine, rat), supplier, Galanin, receptor, agonists, peptide, GAL, GalR, Galanin, Receptors, Galanin, Receptors, Tocris Bioscience

1 Citation for Galanin (1-15) (porcine, rat)

Citations are publications that use Tocris products. Selected citations for Galanin (1-15) (porcine, rat) include:

Millòn et al (2014) A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats. Int.J.Neuropsychopharmacol. 18 PMID: 25522404


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